Clinical Manifestations.

Background: Accelerated long-term forgetting (ALF) is a form of episodic memory impairment where information is retained normally over 30-60 minutes but lost at an accelerated rate over subsequent days to weeks, and is a very early - perhaps the earliest - cognitive change in both autosomal dominant and sporadic Alzheimer's disease (AD). However, the neuroanatomical changes underlying ALF in AD have remained elusive. We explored associations between ALF and focal cortical thickness in presymptomatic autosomal dominant AD (ADAD).

Hispanic Farmers Experience Shorter EMS Response Times but Longer Emergency Department Length of Stay Following Occupational Injuries.

Background: Agriculture has the highest rate of fatal injuries by sector. Hispanic workers also experience more fatal work injuries than every other minority group combined. Pre-hospital and initial trauma evaluation represent an important marker to understand the impact of a trauma system.

Semaphorin 7a is a biomarker for recurrence in postpartum breast cancer.

Breast cancer is a global health threat and cases diagnosed in women during the years after childbirth, or postpartum breast cancers (PPBCs), have high risk for metastasis. In preclinical murine models, semaphorin 7a (SEMA7A) drives the metastatic potential of postpartum mammary tumors. Thus, we hypothesize that SEMA7A may drive metastasis of PPBC in women.

Cross-talk between SIM2s and NFκB regulates cyclooxygenase 2 expression in breast cancer.

Background: Breast cancer is a leading cause of cancer-related death for women in the USA. Thus, there is an increasing need to investigate novel prognostic markers and therapeutic methods. Inflammation raises challenges in treating and preventing the spread of breast cancer.