Publications by authors named "Chloe Shipton"

Article Synopsis
  • This feasibility study examined collecting and analyzing tear proteins from preterm infants to understand the potential links to retinopathy of prematurity (ROP) and to find possible prognostic markers.
  • Using Schirmer's test and mass spectrometry, researchers collected tear samples from 12 infants scheduled for ROP screening, identifying 701 proteins, including key markers associated with ROP risk.
  • The findings suggest that tear sampling is practical, indicating a need for a larger study to explore its role in identifying ROP and improving understanding of retinal development.
View Article and Find Full Text PDF

We report a man in his 80s who described sudden unilateral loss of vision, resulting in extensive urgent investigations by the accident and emergency department team. Subsequent evaluation of visual acuity with pinhole demonstrated significant improvement, triggering further questioning. It transpired that he was mistakenly wearing his wife's glasses, which accounted for his visual symptoms.

View Article and Find Full Text PDF

A 44-year-old male presented with unilateral sudden onset reduced visual acuity. The optical coherence tomography (OCT) scan demonstrated submacular fluid with thickening and hyper-reflectivity of the outer retinal layers, together with subfoveal retinal pigment epithelial hyper-reflectivity corresponding to a small area of foveal interdigitation zone/ellipsoid zone (IZ/EZ) loss in the detached retina. An OCT 4 months later showed resolution of the submacular fluid, but the IZ/EZ loss persisted with thinning of the outer nuclear layer, resulting in a poor visual outcome.

View Article and Find Full Text PDF

Background/objectives: Anterior segment optical coherence tomography (AS-OCT) can be used to visualise keratic precipitates (KPs) on the corneal endothelium. However, there has been no correlation between characteristic clinical appearances of KPs and AS-OCT morphology. We wished to assess the potential diagnostic role of AS-OCT in patients presenting with inflammatory eye disease and KPs.

View Article and Find Full Text PDF