Theranostic Gallium Siderophore Ciprofloxacin Conjugate with Broad Spectrum Antibiotic Potency.

Pathogenic bacteria scavenge ferric iron from the host for survival and proliferation using small-molecular chelators, siderophores. Here, we introduce and assess the gallium(III) complex of ciprofloxacin-functionalized desferrichrome () as a potential therapeutic for bacterial infection using an in vitro assay and radiochemical, tracer-based approach. Ga- exhibits a minimum inhibitory concentration of 0.