Publications by authors named "Chloe Parker"
J Clin Endocrinol Metab
November 2024
Article Synopsis
- Polycystic ovary syndrome (PCOS) is a common hormonal disorder linked to infertility, and its symptoms overlap with those of partial lipodystrophy, which is caused by variations in the LMNA gene.
- Researchers conducted genetic sequencing on two cohorts, comparing PCOS patients with healthy controls to investigate a potential connection between LMNA variations and the development of PCOS.
- Results showed a significant association between rare LMNA variants and PCOS in multiple cohorts, particularly among women exhibiting high triglycerides and insulin resistance, indicating a need to explore further genetic links to PCOS.
