Publications by authors named "Chloe J Kim"
Clin Cancer Res
July 2020
Article Synopsis
- - The study investigates the genomic factors related to clinical outcomes in metastatic castration-sensitive prostate cancer, aiming to clarify how these factors influence disease progression and treatment responses.
- - In a cohort of 424 patients, findings showed that high-volume disease (≥4 bone or visceral metastases) corresponded to increased rates of castration resistance and mortality, with specific genomic alterations being more prevalent in these cases.
- - Key pathways, such as NOTCH and cell cycle, were highlighted as significant in high-volume disease, suggesting that understanding these genomic features can improve molecular classification and guide treatment decisions for affected patients.
