Publications by authors named "Chizuru Hamada"
Article Synopsis
- The study investigates the risk of acute exacerbation (AE) after lung surgery in lung cancer patients who also have interstitial lung disease (ILD), focusing on comorbidities beyond ILD.
- Out of 68 patients evaluated, 11.8% experienced postoperative AEs, with factors like performance status, honeycombing, forced vital capacity, and high hemoglobin A1c levels showing significant associations with these complications.
- The findings suggest that while preoperative comorbidities aside from ILD don't predict AEs, high HbA1c, poor performance status, low lung function, and honeycombing are key risk indicators for AEs following lung resection in patients with lung cancer and ILD.
Osteopontin (OPN) is a multifunctional protein that plays important roles in cell growth, differentiation, migration and tissue fibrosis. In human idiopathic pulmonary fibrosis and murine bleomycin-induced lung fibrosis, OPN is upregulated in type II alveolar epithelial cells (AEC II). However, the mechanism of OPN induction in AEC II is not fully understood.
View Article and Find Full Text PDFExaggerated blood pressure (BP) response to mental stress has been known to be a prognostic factor for cardiovascular disease. It has been argued that such unusual vascular reactivity to mental stress may arise from insulin resistance. To examine the vascular responses to mental stress, we evaluated the stress-related changes in BP and the augmentation index (AI), an index of arterial stiffness, in normotensive young males.
View Article and Find Full Text PDF