Association of cesarean section with asthma in children/adolescents: a systematic review and meta-analysis based on cohort studies.

Background: Whether cesarean section (CS) is a risk factor for asthma in offspring is controversial. The purpose of this study was to investigate the association between CS and asthma in children/adolescents.

Methods: Pubmed, Embase, Web of Science, and Cochrane Library electronic databases were searched for cohort studies on the relationship between mode of delivery and asthma in children/adolescents up to February 2023.

A meta-analysis of application of PD-1/PD-L1 inhibitor-based immunotherapy in unresectable locally advanced triple-negative breast cancer.

The purpose of this study was to explore the efficacy of immunotherapy for patients with triple-negative breast cancer (TNBC). Randomized clinical trials comparing immunotherapy with chemotherapy for advanced TNBC patients were included. A total of six articles (3183 patients) were eligible for this meta-analysis.

Effect of cesarean section on the risk of autism spectrum disorders/attention deficit hyperactivity disorder in offspring: a meta-analysis.

Purpose: This study was conducted to investigate the relationship between cesarean section (CS) offspring and autism spectrum disorders (ASD)/attention deficit hyperactivity disorder (ADHD).

Methods: Searching of the databases (PubMed, Web of Science, Embase, and Cochrane Library) for studies on the relationship between mode of delivery and ASD/ADHD until August 2022. The primary outcome was the incidence of ASD/ADHD in the offspring.

The effect and safety of CDK4/6 inhibitors combined endocrine therapy on HR+, HER2-breast cancer: a meta-analysis of randomized controlled trials.

Introduction: The purpose of this meta-analysis is to evaluate the efficacy and safety of cyclin-dependent kinase4/6 inhibitors (CDK4/6i) combined with endocrine therapy (ET) on hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) breast cancer (BC).

Material And Methods: A search was conducted in the PubMed, Embase, Web of Science, and Cochrane Library databases before July 2022.

Results: A total of 19 studies comprising 19,004 patients were eligible for this meta-analysis.

The relationship between tobacco and breast cancer incidence: A systematic review and meta-analysis of observational studies.

Background: The effect of tobacco on breast cancer (BC) is controversial. The purpose of this study was to investigate the relationship between tobacco and BC.

Methods: A search was conducted in PubMed, EBSCO, Web of Science and Cochrane Library databases before February 2022.

Association of cesarean section with risk of childhood leukemia: A meta-analysis from an observational study.

Recent studies suggest that children born via cesarean section (CS) are predisposed to immune-mediated diseases later in life. The association between CS and childhood leukemia was investigated in this meta-analysis of observational studies. Two researchers independently searched PubMed, Web of Science, Embase, and Cochrane Library for literature on the association between CS and childhood leukemia before February 2022.

De novo motif discovery facilitates identification of interactions between transcription factors in Saccharomyces cerevisiae.

Motivation: Gene regulation involves complicated mechanisms such as cooperativity between a set of transcription factors (TFs). Previous studies have used target genes shared by two TFs as a clue to infer TF-TF interactions. However, this task remains challenging because the target genes with low binding affinity are frequently omitted by experimental data, especially when a single strict threshold is employed.

Predicting protein-protein interactions in unbalanced data using the primary structure of proteins.

Background: Elucidating protein-protein interactions (PPIs) is essential to constructing protein interaction networks and facilitating our understanding of the general principles of biological systems. Previous studies have revealed that interacting protein pairs can be predicted by their primary structure. Most of these approaches have achieved satisfactory performance on datasets comprising equal number of interacting and non-interacting protein pairs.

The 3D scanner for measuring body surface area: a simplified calculation in the Chinese adult.

Three-dimensional (3D) surface anthropometry enables us to extend the study to 3D geometry and morphology of mainly external human body tissues. A model is presented for estimation of human body surface area (BSA), which is identical in form to the one proposed in 1916 by DuBois and DuBois is presented. The purpose of this study is to measure BSA, using 3D scanner, and to derive a simple BSA estimation formula for the Chinese adults.