Biomimetic cell culture for cell adhesive propagation for tissue engineering strategies.

Biomimetic cell culture, which involves creating a biomimetic microenvironment for cells by engineering approaches, has aroused increasing interest given that it maintains the normal cellular phenotype, genotype and functions displayed . Therefore, it can provide a more precise platform for disease modelling, drug development and regenerative medicine than the conventional plate cell culture. In this review, initially, we discuss the principle of biomimetic cell culture in terms of the spatial microenvironment, chemical microenvironment, and physical microenvironment.

Recent Research Progress of F Magnetic Resonance Imaging Probes: Principle, Design, and Their Application.

Visualization of biomolecules, cells, and tissues, as well as metabolic processes in vivo is significant for studying the associated biological activities. Fluorine magnetic resonance imaging ( F MRI) holds potential among various imaging technologies thanks to its negligible background signal and deep tissue penetration in vivo. To achieve detection on the targets with high resolution and accuracy, requirements of high-performance F MRI probes are demanding.