Sensitivity of multiple first trimester sonomarkers in fetal aneuploidy detection.

Background: Multiple first trimester aneuploidy sonomarkers have been introduced recently.

Objective: To evaluate the efficacy of first trimester sonomarkers in fetal aneuploidy detection without serum markers.

Methods: There were entirely 280 fetuses with 11-13+6 weeks' gestation (crown-rump -length between 45-84 mm) enrolled to assess nuchal translucency thickness (NT), nasal bone (NB), tricuspid regurgitation (TR) and ductus venosus (DV) flow.