Formulation of a Novel Polymeric Hydrogel Membrane for Periodontal Tissue Regeneration Using Tricalcium Phosphate-Alginate Reinforcement.

Background: The primary goal of periodontal therapy is to facilitate the regeneration of tissues damaged by periodontal disease. In recent years, there has been a growing utilization of guided tissue regeneration (GTR) membranes with bioabsorbable properties as these membranes are increasingly employed to guide the growth of gingival tissue away from the root surface. Both resorbable and non-resorbable membranes currently employed act as physical barriers, preventing the ingrowth of connective and epithelial tissues into the defect and thereby facilitating periodontal tissue regeneration.

Fluorescence Resonance Energy Transfer in a Supramolecular Assembly of Luminescent Silver Nanoclusters and a Cucurbit[8]uril-Based Host-Guest System.

The understanding of interactions between organic chromophores and biocompatible luminescent noble metal nanoclusters (NCs) leading to an energy transfer process that has applications in light-harvesting materials is still in its nascent stage. This work describes a photoluminescent supramolecular assembly, made in two stages, employing an energy transfer process between silver (Ag) NCs as the donor and a host-guest system as the acceptor that can find potential applications in diverse fields. Initially, we explored the host-guest chemistry between a cationic guest ethidium bromide and cucurbit[8]uril host to modulate the fluorescence property of the acceptor.

Synergistic effect on the performance of ash-based bricks with glass wastes and granite tailings along with strength prediction by adopting machine learning approach.

The study proposes a novel and sustainable method to appropriately utilize wastes from granite as well as glass industries in brick manufacturing. An ecofriendly and low-cost manufacturing process of ash-based bricks pertaining to the Indian standard codal provisions that can be adopted on the commercial scale is deliberated. The research also recommends the method for predicting the strength of the ash-based bricks using machine learning algorithms like random forests and decision trees.

Endophytic Phomopsis sp. colonization in Oryza sativa was found to result in plant growth promotion and piperine production.

Endophytic fungi have been reported to have the acquired ability to synthesize host plant specific medicinal natural products. Many fungi with such properties have been characterized and optimized for the conditions which favor maximal production of desired products. However, the inherent plant colonization property of promising endophytic fungi is least studied.

Spatial changes of estuary in Ernakulam district, Southern India for last seven decades, using multi-temporal satellite data.

The study area, located in the western side of Kerala State, South India, is a part of Vembanad-Kol wetlands - the largest estuary in India's western coastal wetland system and one of the Ramsar Sites of Kerala. Major portion of this estuary comes under the Ernakulam district which includes the Cochin City - the business and Industrial hub of Kerala, which has seen fast urbanization since independence (1947). Recently, this region is subjected to a characteristic fast urban sprawl, whereas, the estuarine zone is subjected to tremendous land use/land cover changes (LULC).

Effectiveness of myofascial release in the management of chronic low back pain in nursing professionals.

Objective: To investigate whether Myofascial release (MFR) when used as an adjunct to specific back exercises (SBE) reduces pain and disability in chronic low back pain (CLBP) in comparison with a control group receiving a sham Myofascial release (SMFR) and specific back exercises (SBE) among nursing professionals.

Design: Randomized, controlled, single blinded trial.

Setting: Nonprofit research foundation clinic in Kerala, India.

Effectiveness of myofascial release in the management of plantar heel pain: a randomized controlled trial.

Background: Previous studies have reported that stretching of the calf musculature and the plantar fascia are effective management strategies for plantar heel pain (PHP). However, it is unclear whether myofascial release (MFR) can improve the outcomes in this population.

Objective: To investigate whether myofascial release (MFR) reduces the pain and functional disability associated with plantar heel pain (PHP) in comparison with a control group receiving sham ultrasound therapy (SUST).

LC-MS/MS based identification of piperine production by endophytic Mycosphaerella sp. PF13 from Piper nigrum.

Piper nigrum is very remarkable for its medicinal properties due to the presence of metabolites like piperine. Emerging understanding on the biosynthetic potential of endophytic fungi suggests the possibility to have piperine producing fungi in P. nigrum.

Piperine production by endophytic fungus Colletotrichum gloeosporioides isolated from Piper nigrum.

Many endophytic fungi have been reported with the biosynthetic potential to produce same or similar metabolites present in host plants. The adaptations that might have acquired by these fungi as a result of the long-term association with their host plants can be the possible basis of their biosynthetic potential. The bioactive compounds originated from endophytes are currently explored for their potential applications in pharmaceutical, agriculture and food industries.

Effectiveness of myofascial release in the management of lateral epicondylitis in computer professionals.

Objective: To investigate whether myofascial release (MFR) reduces the pain and functional disability of lateral epicondylitis (LE) in comparison with a control group receiving sham ultrasound therapy in computer professionals.

Design: Randomized, controlled, single blinded trial.

Setting: Nonprofit research foundation clinic in Kerala, India.

Monilethrix.

Monilethrix is rare hereditary disorder which is in herited as autosomal dominant trit. We report two siblings with a combination of monilethrix and leukonychia.