Publications by authors named "Chitan Keita"
Background: Millions of pyrethroid LLINs have been distributed in Mali during the past 20 years which, along with agricultural use, has increased the selection pressure on malaria vector populations. This study investigated pyrethroid resistance intensity and susceptible status of malaria vectors to alternative insecticides to guide choice of insecticides for LLINs and IRS for effective control of malaria vectors.
Methods: For 3 years between 2016 and 2018, susceptibility testing was conducted annually in 14-16 sites covering southern and central Mali.
Article Synopsis
- - The study aimed to evaluate the level of insecticide resistance in Anopheles gambiae populations in Mali, focusing on the effectiveness of four types of insecticides (organochlorines, pyrethroids, carbamates, and organophosphates) used for malaria control.
- - Researchers used the WHO tube test to measure resistance and employed PCR technology to identify resistance-related genetic mutations, alongside biochemical assays for enzyme activity.
- - Findings indicated widespread and high levels of resistance to DDT, deltamethrin, and lambda-cyhalothrin across various sites in southern Mali, along with the identification of specific mosquito species demonstrating high frequencies of resistance mutations.