Publications by authors named "Chiswili Yves Chabu"
Article Synopsis
- Developmental biology isn't as popular or well-funded as it used to be, and other science fields are getting more attention instead.
- A group of scientists from different parts of developmental biology met to discuss problems that are slowing down new discoveries and to suggest ways to fix them.
- They want to "rebrand" the field, get more funding, encourage teamwork between different science areas, improve how science is taught, communicate better, and make sure everyone has equal opportunities and resources.
Pancreatic cancer (PaC) is resistant to immune checkpoint therapy, but the underlying mechanisms are largely unknown. In this study, we have established four orthotopic PaC murine models with different PaC cell lines by intra-pancreatic inoculation. Therapeutic examinations demonstrate that only tumors induced with Panc02-H7 cells respond to αPD-1 antibody treatment, leading to significantly reduced tumor growth and increased survival in the recipient mice.
View Article and Find Full Text PDFOncogenic RAS mutations are associated with tumor resistance to radiation therapy. Cell-cell interactions in the tumor microenvironment (TME) profoundly influence therapy outcomes. However, the nature of these interactions and their role in Ras tumor radioresistance remain unclear.
View Article and Find Full Text PDFHow organisms control organ size is not fully understood. We found that Syd/JIP3 is required for proper wing size in Drosophila. JIP3 mutations are associated with organ size defects in mammals.
View Article and Find Full Text PDF