Publications by authors named "Chisom Akunna"
Objective: To compare the cardiovascular and renal outcomes of GLP-1 RA versus DPP4i and basal insulin in the management of T2DM.
Methods: Data from 22 studies involving over 200,000 participants were pooled using the inverse variance method and random-effects meta-analysis. The review was reported in accordance with PRISMA.
Reliable estimates of subnational vaccination coverage are critical to track progress towards global immunisation targets and ensure equitable health outcomes for all children. However, conflict can limit the reliability of coverage estimates from traditional household-based surveys due to an inability to sample in unsafe and insecure areas and increased uncertainty in underlying population estimates. In these situations, model-based geostatistical (MBG) approaches offer alternative coverage estimates for administrative units affected by conflict.
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- HIV/AIDS remains a significant public health issue in sub-Saharan Africa, with current efforts falling short of global targets for eradication set by UNAIDS and the SDGs.
- The study utilized extensive data from various HIV prevalence surveys to estimate localized HIV infection rates across 43 African countries, focusing on specific age and sex groups from 2000 to 2018.
- Findings revealed wide disparities in HIV prevalence within countries and districts, indicating that age and sex stratification provides more nuanced insights into the epidemic, which can help tailor prevention and treatment efforts more effectively.
Article Synopsis
- The GBD 2019 study systematically estimated the global cancer burden, providing data on incidence, mortality, and disability to help address cancer worldwide.
- In 2019, an estimated 23.6 million new cancer cases and 10 million cancer deaths occurred globally, marking significant increases in rates since 2010, with cancer becoming a leading cause of both death and disability-adjusted life years (DALYs).
- The impact of cancer varied across sociodemographic index (SDI) quintiles, with higher SDI areas seeing more new cases, while middle SDI areas experienced more deaths and DALYs, highlighting disparities in cancer burden.