Leaf Extract Improves Hepatic Glucose and Lipid Metabolism in Obese Mice Fed with High-Fat Diet.

(MC) is a popular herb used to flavor food in Thailand that exhibits several biological effects. The present study aimed to determine the role of MC in regulating glucose and lipid metabolism in mice fed a high-fat diet (HFD). ICR obese mice were fed an HFD (45 kcal% lard fat) for 12 weeks, with MC (100 and 200 mg/kg/d) treatment from Week 7.

Antibacterial activity of crude extracts of prasaprohyai formula and its components against pathogenic bacteria.

Background: Prasaprohyai formula is a Thai Traditional Medicine which has been used for reducing feverish in child. Fever is a symptom resulting from various infections and diseases. The major cause of fever is bacterial and viral infections.

Antibacterial activity of Thai medicinal plants Pikutbenjakul.

Background: Bacterial infections caused by resistant strains have been increased dramatically. Pikutbenjakul, a Thai medicinal plant formula containing Piper longum, Piper sarmentosum, Piper interruptum, Plumbago indica and Zingiber officinale have been widely used in Thai traditional medicine.

Objective: To determine antimicrobial activity of Pikutbenjakul formula and its components in order to develop the medicinal plants for alternative treatment of bacteria causing diarrhea.

Antibacterial and antifungal activities from Siamese crocodile blood.

Objective: To evaluate the in vitro antimicrobial activity of the Siamese crocodile blood against bacteria and fungi.

Material And Method: Thirty Siamese crocodile blood samples including freeze dried whole blood (FDWB), fresh serum (FS), and freeze dried serum (FDS) were evaluated for antimicrobial susceptibility and MIC values against ATCC-registered strains of nine bacterial species and two fungal species and one fungus isolated from a clinical specimen, by using the standard broth microdilution method and a modified resazurin microtiter plate assay.

Results: The result showed that FS (80 mg/ml) and FDS (100 mg/ml) inhibited Gram negative bacteria including Enterobacter aerogenes ATCC 13048, Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 27736, Salmonella typhimurium ATCC 13311 and Pseudomonas aeruginosa ATCC 27853 with the susceptibility rate at 23.