Publications by authors named "Chirstian Trahan"
Nucleic Acids Res
October 2022
Article Synopsis
- RbgA is a crucial protein for assembling the 50S ribosomal subunit in Bacillus subtilis, and its depletion results in the buildup of an incomplete 45S intermediate.
- Mutant strains with a variant of RbgA that has lower GTPase activity lead to the formation of unique 44S intermediates, indicating different maturation pathways for ribosomal components.
- Analysis of these 44S intermediates shows that while RbgA aids the proper folding and maturation order of functional sites, in its absence, the components can mature in a more flexible and less structured manner.
