Inflatable penile prosthesis and salvage protocol for mechanical failure: is it really necessary?

Introduction: Penile prosthesis patients with mechanical failure who wish continued treatment require device removal and replacement. Infection rates as high as 18% have been reported for procedures involving replacement of malfunctioning penile prosthesis compared with 2% for primary implantation.

Aim: The aim of this study is to compare the outcomes of patients who have had a penile prosthesis replacement for mechanical failure to determine if those who had a mini-salvage washout procedure had better outcomes than those who did not.

Infection rates of rifampin/gentamicin-coated Titan Coloplast penile implants. Comparison with Inhibizone-impregnated AMS penile implants.

Introduction: It is a common practice to soak Titan(®) Coloplast penile implants in antibiotic solution prior to implantation. Experience with Inhibizone impregnation suggests that rifampin coating significantly reduces infection rates of penile implant surgery. In this article we describe the results of coating Titan Coloplast penile implants with rifampin/gentamicin solution.

In vitro assessment of antimicrobial properties of rifampin-coated Titan(®) Coloplast penile implants and comparison with Inhibizone(®).

Introduction: It is a common practice to soak Titan(®) Coloplast penile implants in antibiotic solution prior to implantation. Aim.  The aim of this study is to identify an ideal solution for soaking the Titan(®) Coloplast penile implants prior to implantation.

Antibiotic soaked hydrophilic coated bioflex: a new strategy in the prevention of penile prosthesis infection.

Objectives: To find conditions that reduce the susceptibility of penile prostheses to infection, we studied the effect of coating the surface of polyurethane (Bioflex) with a hydrophilic material with and without antibiotics in decreasing bacterial colony counts both in vitro and in experiments in rats.

Materials And Methods: The in vitro experiment was performed using seven strips each of polyvinylpyrrolidone (PVP)-coated and uncoated polyurethane. These strips were dipped in saline for 5 minutes followed by incubation in a suspension of Staphylococcus epidermidis (SE) for a period of 10 minutes.

Multiple retained needles: an unusual complication of intracavernous self-injection.

Intracavernous self-injection of pharmacologic agents is an effective method of treatment of erectile dysfunction. Intracorporeal needle breakage is a rare complication of intracavernosal self-injection. We report an unusual case of multiple retained needles in a 44-year-old man who presented with penile edema after intracavernous self-injection complicated by needle breakage.

Effects of C-peptide on expression of eNOS and iNOS in human cavernosal smooth muscle cells.

Objectives: To investigate the role of C-peptide alone or in conjunction with insulin on the expression of nitric oxide synthase (NOS) in human corpus cavernosum smooth muscle cells (HCSMCs). Erectile dysfunction, among diabetic patients, is a significant health problem. The specific causes of erectile dysfunction are unknown.

Fate of the retained reservoir after replacement of 3-piece penile prosthesis.

Purpose: We evaluated patients who underwent surgery for implant malfunction to determine whether retaining the reservoir was associated with an increased risk of erosion or infection. We also reviewed the literature to study possible risk factors for reservoir erosion.

Materials And Methods: We reviewed the records of 85 patients who underwent 98 procedures for replacement of a malfunctioning 3-piece penile implant.

Comparison of satisfaction rates and erectile function in patients treated with sildenafil, intracavernous prostaglandin E1 and penile implant surgery for erectile dysfunction in urology practice.

Purpose: We compared erectile function status and satisfaction rates in patients who received treatment for erectile dysfunction (ED) with sildenafil, intracavernous prostaglandin E1 (ICI) and penile implant surgery (IPP).

Materials And Methods: A total of 138 consecutive patients who received treatment for ED between April 2000 and April 2001 were considered candidates for study. Mean followup was 19.

Deep venous thrombosis due to compression of external iliac vein by the penile prosthesis reservoir.

Penile implant surgery has a high rate of success and a very high patient satisfaction rate. Compression of the external iliac vein by the reservoir of the penile implant is an extremely rare occurrence. We describe a case of deep vein thrombosis due to compression of the external iliac vein, which required replacement of the penile implant reservoir.