Publications by authors named "Chirkin V"

During 50 days a group of 23 volunteers received lunches prepared on the basis of textured proteins of soy beans. Each lunch included 50 g of proteins. Laboratory investigation was carried on dynamic values of lipid metabolism, cell-mediated, humoral and local immunity.

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71 patients with nonspecific diseases of the colon were examined before and after hemosorption for concentrations of seromucoid, orosomucoid, immunoglobulins G,M,A, C3 and C4 complement component fractions, haptoglobin, ceruloplasmin, alpha 1-antitrypsin, C-reactive protein, properdin, transferrin. It was found that hemosorption results in lowering of all the above concentrations in nonspecific ulcerative colitis, except seromucoid and orosomucoid in moderate and acute colitis. In response to hemosorption serum glycoproteins levels varied with the disease severity, its duration and metabolic activity of the liver.

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A principal block scheme of an apparatus complex is suggested and a method for examination of masticatory muscle function is described. The method is based on electrostimulation of masticatory nerve followed by registration and analysis of the masticatory muscle action evoked potentials. The block scheme of the apparatus complex includes a universal electrostimulator ESU-2.

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Principal block-diagram and characteristics of devices recording the parameters of periodontal muscular reflex in humans are presented. Twenty healthy volunteers aged 20 to 30 years with full dentition and normal occlusion and temporomandibular articulations unchanged were studied. Parameters of periodontal muscular reflex showed no bilateral asymmetry.

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Results of treatment of 32 patients with phlegmons of the face and neck with the use of reinfusion of UV irradiated blood (RUVIB) are presented. RUVIB was found to exert positive influence upon metabolic processes and thus it created the optimum conditions for the functioning of the immune system improving the clinical effects of the treatment.

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The authors analyzed immunological changes in 56 patients with chronic colon stasis at the compensated and decompensated stages. Clinicoimmunological investigation of these patients permitted the detection of considerable changes in the system of homeostasis against a background of chronic inflammation of the colon mucous membrane, dysbacteriosis, colon microflora, and intoxication. Signs of secondary immunodeficiency with simultaneous involvement of compensatory mechanisms of nonspecific and specific body defence were noted in the patients.

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One hundred and seven sessions of hemosorption were performed on 77 patients with severe ulcerative colitis. Clinically, improvement was demonstrated in the reduction of the signs of intoxication in 50 to 60 per cent of patients. Combination of hemosorption and anti-inflammatory medication allowed to achieve a remission or a marked improvement determined by clinical observation or endoscopy of 39 from 52 patients with a severe, total form of the disease, whereas toxic influence of sulfasalazine was controlled and extra-intestinal complications were weakened in 8 patients from 11.

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