Newborn hearing screening programme based on an integrated hospital and community care system. Results of the first 4 years of activity.

Since January 2012, babies born in the province of Modena, Italy, have routinely undergone hearing testing as part of a two-stage screening programme. Newborn hearing screening (NHS) has been based on an integrated hospital and community care system and this study aims to assess screening coverage, referral rates, the prevalence, type and extent of hearing loss several years into the programme. Data were collected from January 1, 2012 to December 31, 2015.

Neonatal pyknocytosis in a preterm dizygotic twin.

Infantile pyknocytosis (IP) is a rare, self-limited neonatal haemolytic anaemia that may require multiple blood transfusions. Only a little more than 50 cases have been reported in the medical literature, and the great majority of them concerns term infants. The etiology of IP is not well understood; most likely it results from a transient extra-corpuscular factor, whose nature is unknown, transmitted from mother to child or, alternatively, from a deficiency of an anti-oxidative agent.

An area-based study on intrapartum antibiotic prophylaxis for preventing group B streptococcus early-onset disease: advances and limitations.

Introduction: The prevalence of maternal group-B-streptococcus (GBS) colonization and risk factors (RFs) for neonatal early-onset disease (EOD) in Europe are poorly defined. Large-scale information concerning adherence to recommendations for preventing GBS-EOD are lacking.

Materials And Methods: This was a 3-month retrospective area-based study including all regional deliveries  ≥35 weeks' gestation (in 2012).

Intrapartum antibiotic prophylaxis failure and group-B streptococcus early-onset disease.

Objectives: To determine factors influencing intrapartum antibiotic prophylaxis (IAP) failure in the prevention of group B streptococcus (GBS) early-onset disease (EOD).

Methods: GBS EOD case is defined as isolation of GBS from a normally sterile body site (e.g.

A study of childhood febrile convulsions with particular reference to HHV-6 infection: pathogenic considerations.

Most febrile convulsions (FC) in infants occur during a viral infection, particularly in children of less than 3 years of age; human herpesvirus 6 (HHV-6) has an important pathogenic role. To evaluate the link between this and other viruses and FC, a group of 65 children (mean age 18.46 months, SD +/- 9.

Ultrasound screening of urinary malformations in 'normal' newborns.

Objectives: To determine: (1) the incidence in newborns of both significant urinary anomalies and mild hydronephrosis; (2) the degree of inaccuracy of prenatal sonography in our area, and (3) the evolution of neonatal hydronephrosis.

Methods: Using ultrasound, we examined 4,130 consecutive newborns, of which only 12 had a positive prenatal sonography. We distinguished 2 grades of hydronephrosis: mild (pelvic diameter between 5 and 15 mm), and significant (pelvic diameter > 15 mm).

[Osteochondrodysplasia: nosologic assessment and report of 6 clinical cases].

Osteochondrodysplasias represent an important group of disease affecting cartilage and/or bone. The clinical evidence of disarmoniuous low stature, of a disproportion between trunk and limbs length, of a big skull can suggest this diagnosis and the necessity to carry out all the instrumental investigations. The diagnostic suspect can be placed, some time, already in the neonatal period.

[Correlation between plasma IgE and IgA in infant nephrosis and nephrotic syndrome].

A study on IgE - IgA plasmatic level has been carried out in the acute phase and in remission of minimal changes nephrosis (MCN) and in glomerulonephritis with nephrotic syndrome (NS). The results obtained are the following: 1) Mean values of Ig classes were impaired in comparison with the normal values of children of the same age, both in MCN and in NS. 2) IgE were increased, particularly in children over 6 years in the MCN acute phase; the values decreased within normal after the remission was achieved.

[Medical and dietetic management of congenital and inherited nephropathies (author's transl)].

The management of the congenital and inherited nephropathies is, still today, almost exclusively symptomatic. The authors relate the most important drugs and the dose used for the principal complications of these nephropathies: hypertension, hypo-dysprotidoemia, oedema, anemia, metabolic acidosis, polyuria, hypoevolutism, recurrent urinary infections. Particular care must be taken in order to provide an adequate caloric-protein allowance principally when the renal insufficiency is reached.