Publications by authors named "Chinting Wong"

Thyroid cancer (TC) is a common endocrine malignancy with an increasing incidence worldwide. Early diagnosis is particularly important for TC patients, because it allows patients to receive treatment as early as possible. Artificial intelligence (AI) provides great advantages for complex healthcare systems by analyzing big data based on machine learning.

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Accurate and automated segmentation of breast tumors in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) plays a critical role in computer-aided diagnosis and treatment of breast cancer. However, this task is challenging, due to random variation in tumor sizes, shapes, appearances, and blurred boundaries of tumors caused by inherent heterogeneity of breast cancer. Moreover, the presence of ill-posed artifacts in DCE-MRI further complicate the process of tumor region annotation.

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Background: Lymphovascular invasion (LVI) status plays an important role in treatment decision-making in rectal cancer (RC). Intravoxel incoherent motion (IVIM) imaging has been shown to detect LVI; however, making better use of IVIM data remains an important issue that needs to be discussed.

Purpose: We proposed to explore the best way to use IVIM quantitative parameters and images to construct radiomics models for the noninvasive detection of LVI in RC.

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To develop and validate the predictive effects of stable ferroptosis- and pyroptosis-related features on the prognosis and immune status of breast cancer (BC). We retrieved as well as downloaded ferroptosis- and pyroptosis-related genes from the FerrDb and GeneCards databases. The minimum absolute contraction and selection operator (LASSO) algorithm in The Cancer Genome Atlas (TCGA) was used to construct a prognostic classifier combining the above two types of prognostic genes with differential expression, and the Integrated Gene Expression (GEO) dataset was used for validation.

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Article Synopsis
  • - A 61-year-old man experienced urinary and defecation issues for 4 months, leading to an abdominal contrast-enhanced CT that showed large rectal masses suspected to be cancerous and affecting nearby organs.
  • - An 18 F-FDG PET/CT scan was conducted for staging, revealing intense activity in masses involving the rectum, bladder, prostate, left ureter, and abdominal wall in the pelvic area.
  • - Further histopathological analysis identified the masses as malakoplakia, characterized by specific cells (von Hansemann cells) and unique structures known as Michaelis-Gutmann bodies.
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  • The habenula (Hb) plays a key role in various human behaviors, and its size and neural activity changes are linked to psychiatric disorders and addiction, which recent MRI studies have begun to explore.* -
  • Despite its small size, advancements in MRI techniques have improved the ability to study the Hb, although traditional structural imaging methods have limitations in distinguishing the Hb from nearby areas.* -
  • The review emphasizes the importance of using noninvasive MRI methods to better understand the Hb's anatomy and functions, proposing that multiparametric MRI could aid in developing useful imaging markers for diagnosis and treatment.*
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Rectal cancer (RC) accounts for approximately one-third of colorectal cancer (CRC), with death rates increasing in patients younger than 50 years old. Magnetic resonance imaging (MRI) is routinely performed for tumor evaluation. However, the semantic features from images alone remain insufficient to guide treatment decisions.

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