Anti-cancer activity of leaves explained using its compounds docked with p53.

Extensive research on the mutant P53 protein has identified its pivotal role in anti-apoptosis mechanisms, drug resistance, and cancer progression in OSCC. The mass spectrum revealed the pharmacologically significant bioactive compounds reported for the first time in C cainito. Molecular docking investigation has identified four potential new P53 inhibitors compared with the standard P53 inhibitors.

Optimization of aqueous-assisted extraction of polysaccharides from pumpkin ( Duch) and their biological activities.

The pumpkin pulp contains a greater composition of edible polysaccharides and has reported with excellent biological applications. This research pertains to optimize the extraction of polysaccharides from the fleshy portion of the pumpkin using aqueous assisted extraction (AAE). The result showed that the optimal extraction condition of pumpkin polysaccharide was as follows: extraction temperature at 55 °C, pH 4.

Facile synthesis of gold and platinum doped titanium oxide nanoparticles for antibacterial and photocatalytic activity: A photodynamic approach.

A simple method has been needed to synthesize nanoparticles (NPs) to avoid environmental pollution, an alternative chemical and physical method. This current study deals with phytosynthesis of gold (Au) and platinum (Pt) metal doped with titanium oxide (TiO) NPs using Enterolobium saman bark extract. This extract plays a vital role in reducing and stabilizing Au and Pt doped into the TiO NPs lattices.

Green synthesis of gold nanoparticles using a cheap Sphaeranthus indicus extract: Impact on plant cells and the aquatic crustacean Artemia nauplii.

The impact of green-fabricated gold nanoparticles on plant cells and non-target aquatic species is scarcely studied. In this research, we reported an environment friendly technique for the synthesis of gold nanoparticles (Au NPs) using the Sphaeranthus indicus leaf extract. The formation of the metal NPs was characterized by UV-Visible and FT-IR spectroscopy, XRD, SEM and TEM analyses.