Minimum Corneal Diameter and Anterior Steep Axis Curvature Share the Same Meridian: A Novel Finding.

Purpose: To define the external scleral sulcus (ESS) on a Scheimpflug image and use it for a morphometric analysis of corneal diameter (CD).

Design: Retrospective, cross-sectional study of pediatric Asian-Indian eyes.

Methods: One random eye of 353 subjects between 5 and 18 years underwent 25-scan Pentacam HR imaging.

New simulation software to predict postoperative corneal stiffness before laser vision correction.

Purpose: To develop a new virtual surgery simulation platform to predict postoperative corneal stiffness (Kc mean ) after laser vision correction (LVC) surgery.

Setting: Narayana Nethralaya Eye Hospital and Sankara Nethralaya, India; Humanitas Clinical and Research Center, Italy.

Design: Retrospective observational case series.

Surgical technique for the management of corneal perforation in brittle cornea.

Brittle cornea syndrome is among the few special scenarios in ophthalmology that are a nightmare not only for the operating surgeon but also for the patient. Here, the thin and fragile corneas are unable to maintain the shape and structural integrity of the globe and are more prone to minor traumatic or spontaneous corneal perforations. Suturing a brittle cornea and closure of the corneal perforation in a brittle cornea are very challenging requiring the utmost care and special precautions.

Long-term outcome of custom toric intraocular lens for treating high astigmatism in case of cataract associated with pellucid marginal corneal degeneration.

Pellucid marginal corneal degeneration (PMCD) is a progressive corneal ectasia that ultimately results in high regular astigmatism and correction of this astigmatism is always challenging. However, when a PMCD patient develops a cataract, it provides a golden opportunity to treat this coexisting astigmatism with toric intraocular lens (IOL) implantation. Regular toric IOLs would correct astigmatism only up to 6 diopters in the IOL plane but higher astigmatism would require customization of such IOLs.

Unique corneal tomography features of allergic eye disease identified by OCT imaging and artificial intelligence.

The purpose of this study was to assess unique corneal tomographic parameters of allergic eye disease (AED) using optical coherence tomography (OCT) and artificial intelligence (AI). A total of 57 eyes diagnosed with AED were included. The curvature and aberrations of the air-epithelium (A-E) and epithelium-Bowman's layer (E-B) interfaces were calculated.

Repeatability of OCT Anterior Surface and Bowman's Layer Curvature and Aberrations in Normal and Keratoconic Eyes.

Purpose: To study the repeatability of anterior surface and Bowman's layer curvature in normal and keratoconic eyes using optical coherence tomography (OCT).

Methods: In this study, 96 normal and 96 keratoconic eyes underwent corneal imaging using Pentacam (Oculus Optikgeräte, Wetzlar, Germany) and OCT (Triton, Topcon Corporation, Tokyo, Japan). The elevation data from segmented air-epithelium (A-E) and epithelium-Bowman's layer (E-B) interfaces in OCT scans were used to quantify curvature and aberrations.

Temporal Regulation of Notch Signaling and Its Influence on the Differentiation of Cultured Limbal Epithelial Cells.

: Notch signaling plays a vital role in the differentiation and proliferation of corneal epithelial cells from limbal stem cells. The temporal regulation of Notch signaling during this differentiation remains unknown. Hence, we investigated the importance of temporal activation/blockage of Notch signaling during corneal differentiation.

Corneal staining during cataract surgery: Natural course, ASOCT features, and preventive measures.

We report the natural course of the accidental injection of trypan blue into the corneal stroma while performing a routine cataract surgery by a resident during a training session. The corneal staining resolved with conservative medical treatment over 7 weeks. This case describes the anterior segment optical coherence tomography (ASOCT) features of corneal staining.

Wavefront-Guided LASIK Has Comparable Ocular and Corneal Aberrometric Outcomes but Better Visual Acuity Outcomes Than SMILE in Myopic Eyes.

Purpose: To compare ocular and corneal aberrometric outcomes of wavefront-guided (WFG) LASIK and small incision lenticule extraction (SMILE).

Methods: This was a prospective, interventional study where 48 eyes (24 patients) underwent SMILE (Carl Zeiss Meditec, Jena, Germany) and 58 eyes (29 patients) underwent WFG LASIK (Abbott Medical Optics, Abbott Park, IL). Visual acuity and ocular surface disease index were assessed preoperatively and 1 and 3 months postoperatively.

Correlation between tear fluid and serum vitamin D levels.

Background: Vitamin D deficiency is associated with a range of systemic diseases including ocular disorders. The objective of this study is to measure tear vitamin D levels and investigate the correlation between serum and tear vitamin D levels.

Methods: A total of 48 healthy volunteers without any systemic and ocular disease were recruited for this observational cohort study.