Publications by authors named "Chinmay Kalluraya"
Natural selection drives the acquisition of organismal resilience traits to protect against adverse environments. Horizontal gene transfer (HGT) is an important evolutionary mechanism for the acquisition of novel traits, including metazoan acquisitions in immunity, metabolic, and reproduction function via interdomain HGT (iHGT) from bacteria. Here, we report that the nematode gene rml-3 has been acquired by iHGT from bacteria and that it enables exoskeleton resilience and protection against environmental toxins in Caenorhabditis elegans.
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- Natural selection helps organisms develop traits that protect them from tough environments, like toxins.
- Nematodes, a type of tiny worm, gained a special gene from bacteria that helps them strengthen their outer covering and resist stress.
- This study shows that a gene from bacteria helps these nematodes make a sugar called L-rhamnose, which keeps their skin strong and helps them survive in hard conditions.
Bacterial origin of a key innovation in the evolution of the vertebrate eye.
Proc Natl Acad Sci U S A
April 2023
The vertebrate eye was described by Charles Darwin as one of the greatest potential challenges to a theory of natural selection by stepwise evolutionary processes. While numerous evolutionary transitions that led to the vertebrate eye have been explained, some aspects appear to be vertebrate specific with no obvious metazoan precursor. One critical difference between vertebrate and invertebrate vision hinges on interphotoreceptor retinoid-binding protein (IRBP, also known as retinol-binding protein, RBP3), which enables the physical separation and specialization of cells in the vertebrate visual cycle by promoting retinoid shuttling between cell types.
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