Feasibility and Advantages of Continuous Synthesis of Bioinspired Silica Using CO as an Acidifying Agent.

In this work, we present a method for the continuous synthesis of bioinspired porous silica (BIS) particles using carbon dioxide (CO) as an acidifying agent. Typical BIS synthesis uses strong mineral acids (e.g.

Novel Machine Learning-Based Method for Estimation of the Surface Area of Porous Silica Particles.

This work reports a novel and quick method to estimate the surface area of porous materials. Conventionally, surface area measurement requires the BET method/N adsorption experiment which is time-consuming. In this work, we developed a method based on machine learning (ML) and the adsorption of a conductive dye on porous materials.

Assessing the possibilities of designing a unified multistep continuous flow synthesis platform.

The multistep flow synthesis of complex molecules has gained momentum over the last few years. A wide range of reaction types and conditions have been integrated seamlessly on a single platform including in-line separation as well as monitoring. Beyond merely getting considered as 'flow version' of conventional 'one-pot synthesis', multistep flow synthesis has become the next generation tool for creating libraries of new molecules.

Automating multistep flow synthesis: approach and challenges in integrating chemistry, machines and logic.

The implementation of automation in the multistep flow synthesis is essential for transforming laboratory-scale chemistry into a reliable industrial process. In this review, we briefly introduce the role of automation based on its application in synthesis viz. auto sampling and inline monitoring, optimization and process control.