Publications by authors named "Chinkuli Munkombwe"
Article Synopsis
- The study focuses on identifying early biomarkers for Alzheimer's disease in a diverse group of middle-aged individuals, using neuroimaging and cerebrospinal fluid markers.
- Researchers analyzed 76 cognitively healthy participants, comparing biomarkers like amyloid beta (Aβ)42 with brain connectivity and structure.
- Significant findings show that lower Aβ42 in Black Americans correlates with reduced brain connectivity and increased white matter hyperintensities, suggesting these may indicate higher Alzheimer's risk in this group.
It is well known that vascular factors and specific social determinants of health contribute to dementia risk and that the prevalence of these risk factors differs according to race and sex. In this review, we discuss the intersection of sex and race, particularly female sex and Black American race. Women, particularly Black women, have been underrepresented in Alzheimer's disease clinical trials and research.
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