Publications by authors named "Chinh Thi Nguyen"

Article Synopsis
  • - The study evaluated 30 patients with hepatocellular carcinoma (HCC) who underwent right hepatectomy using a combination of two techniques: the extrahepatic Glissonean pedicle approach and liver hanging maneuver, all performed by a single surgeon from March 2020 to August 2023.
  • - Results showed that the majority of patients were male (96.7%) with an average age of 54.9 years; the surgery had a low complication rate, with no transfusions needed and a mean hospital stay of about 9 days, though 43.3% experienced recurrence.
  • - The 1-year, 2-year, and 3-year survival rates post-surgery were 86.1%,
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Lumpy skin disease (LSD) is a transboundary, systemic, viral disease of cattle. The first outbreaks of LSD were reported in Lang Son Province of Vietnam (bordered to China), and an official document has been submitted to OIE on 1 November 2020. Here, we described first the genetic profiles of this pathogen based on four well-known marker regions.

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Since African swine fever virus (ASFV) introduction into Vietnam in 2019, most ASFV strains detected in this country belong to the p72 genotype II and intergenic region (IGR) II variant. Further investigation of the intergenic region of ASFVs isolated in the Capital Hanoi region showed two different variants, IGR I and IGR II, which were located between the I73R and I329L genes of the p72 genotype II ASFV strains. This finding suggests co-circulation of two ASFV variants in the domestic pig population in Vietnam.

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Since the first outbreak of African swine fever virus (ASFV) in China in 2018, the disease has spread to Mongolia, Vietnam, Cambodia, Korea, Laos, Myanmar, Philippines, Timor-Leste, Indonesia and Papua New Guinea. ASFV was officially reported in Vietnam on 19 February 2019. The continued spread of ASFV has occurred in the whole country within 7 months.

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Interleukins (ILs) regulate cell surface antigens known as activation markers, which have distinct functional roles. However, the regulation of major histocompatibility complex (MHC) class I, MHC class II, and related genes by cytokines in chickens is not well understood. In the present study, we evaluated the influence of certain recently discovered chicken interleukins-i.

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Purpose: To date, many kinds of classical swine fever (CSF) vaccines have been developed to protect against this disease. However, the efficacy of these vaccines to protect the pig against field CSF strains needs to be considered, based on circulating strains of classical swine fever virus (CSFV).

Materials And Methods: Recombinant E2-CSFV protein produced by baculovirus/insect cell system was analyzed by western blots and immunoperoxidase monolayer assay.

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Article Synopsis
  • The detection of the African swine fever virus (ASFV) is crucial for managing outbreaks, and modifications in probe sequences can help reduce false negatives in real-time PCR testing.
  • Seven samples were tested, revealing that while the original OIE probe worked well for some, it failed for those with mutations; the modified probe detected ASFV in these cases.
  • This study underscores the need for slight modifications to testing methods to improve accuracy in detecting ASFV in clinical samples, particularly in Vietnam.
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