Publications by authors named "Ching-Yi Cho"

Background: Macrosomia, defined as a birth weight of ≥4000 g, is associated with a high risk of birth injury. Fetal growth is highly correlated with maternal conditions, and several maternal factors are associated with neonatal birth size. The current study aimed to assess maternal factors related to fetal macrosomia in a Taiwanese population.

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  • * Colloidal GNR thin films offer benefits such as a wide operating range and a fast recovery time, with notable parameters including a modulation depth of 7.8% and saturation intensity of 6.55 MW/cm.
  • * The research showcases the successful implementation of these materials in self-starting mode-locked lasers achieving 24.91% efficiency and Q-switched lasers with 0.403 μJ energy, highlighting the potential for reconfigurable all-fiber laser systems
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Background: Enterovirus A71 (EV-A71) infection can cause severe debilitating complications and even death in young children. The immunogenicity and safety of an inactivated whole EV-A71 virus vaccine were assessed in children 2 months to 6 years of age.

Methods: This was an open-label, multi-center and randomized phase IIb study, which divided into part A and B.

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Background: Group B Streptococcus (GBS) infection is one of the major causes of neonatal morbidity and mortality. Universal GBS screening with intrapartum antibiotic prophylaxis (IAP) in pregnant women were initiated in 2012 in Taiwan. This study aimed to analyze the most recent maternal GBS colonization rate and the changes in neonatal GBS infection rate from 2011 to 2016.

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  • Condyloma acuminata, or genital warts, affects about 1% of sexually active adults and is linked to an increased risk of various cancers, particularly those related to human papillomavirus (HPV).
  • A study in Taiwan tracked 21,763 GW patients from 2000 to 2013, finding 1,002 developed cancer, with a significant association to HPV-related cancers and an increased standardized incidence ratio (SIR) of 9.74 for these cancers.
  • The findings suggest that individuals with GW should be prioritized for cancer screening and HPV vaccination to address their heightened cancer risks, especially for anogenital and smoking-related cancers.
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  • The study examines antibiotic prescription trends for acute tonsillitis in children in Taiwan between 2000 and 2009, focusing on group A beta-hemolytic streptococcus as the main culprit for these prescriptions.
  • Data from the National Health Insurance Research Database showed a decrease in antibiotic prescriptions from 28.4% in 2000 to 10.9% in 2009, with variations based on factors like age and physician specialty.
  • The study concludes that while antibiotic prescriptions have declined, it highlights the need for improved diagnostic methods (like rapid tests) to further reduce unnecessary prescriptions.
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Background: Fever of unknown origin (FUO) was first described in 1961 as fever >38.3°C for at least 3 weeks with no apparent source after 1 week of investigations in the hospital. Infectious disease comprises the majority of cases (40-60%).

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  • Antibiotic resistance is a significant global issue, primarily due to the overprescription of antibiotics, especially among children with acute respiratory tract infections (ARTIs).
  • A study in Taiwan analyzed pediatric ambulatory care data from 2000 to 2009, finding that 7.0% of 565,065 children diagnosed with ARTIs were prescribed antibiotics, with a notable decline in prescriptions over the decade.
  • Factors such as age, gender, season, and type of medical facility were linked to lower rates of antibiotic prescriptions, suggesting that targeted interventions could enhance antibiotic stewardship in pediatric care.
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