Elucidating the Phase I metabolism of psilocin in vitro.

Psilocin is a well-studied controlled substance with potential psychotherapeutic applications. However, research gaps remain regarding its metabolism. Our objective was to elucidate a comprehensive Phase I metabolic profile of psilocin to support its forensic management and clinical development.

Qualitative Confirmation of 94 New Psychoactive Substances and Metabolites in Urine Using Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry.

Numerous methods and techniques have been published for the identification of new psychoactive substances (NPS) and their metabolites in urine. However, there lacks a holistic approach to analyze different groups of NPS and their metabolites with decision points for reporting their use. In this study, data-dependent acquisition workflow using liquid chromatography--quadrupole time-of-flight mass spectrometry was developed and validated for the identification of a total of 94 NPS and metabolites in urine using the established decision points.

A comparison of brain phantom relative permittivity with CST simulation library and existing research.

The development of human-like brain phantom is important for data acquisition in microwave imaging. The characteristics of the phantom should be based on the real human body dielectric properties such as relative permittivity. The development of phantom includes the greymatter and whitematter regions, each with a relative permittivity of 38 and 28 respectively at 10 GHz frequency.

Reflection coefficient detection of simulation models for microwave imaging simulation system.

The study was conducted based on two objectives as framework. The first objective is to determine the point of microwave signal reflection while penetrating into the simulation models and, the second objective is to analyze the reflection pattern when the signal penetrate into the layers with different relative permittivity, εr. Thus, several microwave models were developed to make a close proximity of the in vivo human brain.