Publications by authors named "Chin-Hsi Yeh"
Article Synopsis
- - Since the 1990s, mental illnesses like depression have been rising significantly, highlighting the need for natural therapies due to the side effects of conventional antidepressants.
- - In a study with mice, different doses of chlorella and lion's mane mushroom extracts were administered alongside corticosterone to induce depression, and behavior was monitored using tests like the open field test (OFT) and forced swimming test (FST).
- - Results showed that medium and high doses of the extracts improved depressive behaviors, indicated by increased activity in the OFT, reduced immobility in the FST, and raised levels of brain-derived neurotrophic factor (BDNF), suggesting potential antidepressant effects.
Hot water was used to obtain hot water extract (HWE). Subsequently, this byproduct was freeze-dried, hydrolysed at 50 °C using Protease N to obtain protein hydrolysates (PN-1), and then digested with a gastrointestinal enzyme (PN-1G). The inhibitory effects of the HWE and hydrolysates against angiotensin I-converting enzyme (ACE) were investigated.
View Article and Find Full Text PDFMuch research suggests that a dietary supplement of Chlorella pyrenoidosa may be helpful to human health, but the molecular mechanism involved remains unclear. The aim of this research was to investigate the effects of certain hot-water-soluble polysaccharides from Chlorella pyrenoidosa (CWSP) on cytokine production, human leukocyte antigen (HLA) expression, and costimulatory molecule expression in macrophages. We demonstrated that CWSP induced IL-1beta secretion in macrophages via Toll-like receptor 4 (TLR4) mediated protein kinase signaling pathways.
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