Publications by authors named "Chimezirim Ezeano"
This review investigated the current research on the association between in vitro fertilization and children's neurocognitive development. Twenty studies were analyzed, encompassing over 23,000 children conceived through IVF, and compared to those conceived naturally. The findings on overall cognitive function were mixed, as measured by IQ.
View Article and Find Full Text PDFA review of exercise interventions for reducing anxiety symptoms: Insights and implications.
Medicine (Baltimore)
October 2024
Article Synopsis
- - Generalized anxiety disorder (GAD) is common, and while medications exist, their side effects lead many to explore non-drug treatments like aerobic exercise for managing anxiety symptoms.
- - A narrative review shows that various forms of aerobic exercise (like high-intensity interval training, resistance training, and walking) can effectively reduce anxiety symptoms and enhance well-being in diverse groups, including patients and older adults undergoing cancer treatment.
- - The review discusses the biological and psychological reasons behind the beneficial effects of exercise, while also noting that research limitations and differences in study designs mean the results should be interpreted with caution, highlighting a need for further investigation into optimal exercise types and long-term effects.
Critical illness encompasses the dysfunction of vital organs, the risk of death, and potential reversibility; it is a major cause of morbidity and mortality globally. The pathophysiology underlying many critical illnesses includes bioenergetic failure, inflammation, and oxidative stress. This systematic review aims to explore the use of nutritional ketosis (ketogenic feeds and exogenous ketone body administration) as a potential therapy, affecting the aforementioned pathways in patients with critical illnesses.
View Article and Find Full Text PDFArticle Synopsis
- * Recent advancements in treatment include new RNA interference therapies, Vutrisiran and Eplontersen, which have shown potential in improving symptoms, quality of life, and biological markers in clinical trials.
- * Ongoing research is essential to enhance understanding of these therapies and to explore new treatment options, aiming to better meet the diverse needs of patients affected by ATTRv amyloidosis globally.
Article Synopsis
- * Semaglutide shows promise in improving symptoms, aiding weight management, and possibly boosting exercise capacity, although its effects on heart function and the exact benefits remain unclear.
- * While semaglutide has a generally favorable safety profile, further research is needed to confirm its effectiveness, explore optimal dosages, and understand its mechanisms before establishing it as a standard treatment for HFpEF.
Background: In the United States, racial disparities in health outcomes continue to be a major problem with far-reaching effects on equity in healthcare and public health. Children and teenagers with type 1 diabetes are a disadvantaged demographic that has particular difficulties in managing their condition and getting access to healthcare. Despite improvements in the treatment of diabetes, little study has examined how much racial disparities in in-hospital mortality affect this particular demographic.
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