Ultrasonic-assisted extraction of flavonoids from Nitraria sibirica leaf using response surface methodology and their anti-proliferative activity on 3T3-L1 preadipocytes and antioxidant activities.

As both an edible and medicinal plant, Nitraria sibirica has been used as a natural remedy for indigestion and hypertension since ancient times in Central Asia. The ethanolic extract of N. sibirica leaves lowers blood pressure and blood lipids.

Mussel-Inspired Caries Management Strategy: Constructing a Tribioactive Tooth Surface with Remineralization, Antibiofilm, and Anti-inflammation Activity.

Dental caries is a common chronic oral disease in humans resulting from tooth demineralization caused by acid production of bacterial plaque, which leads to the destruction of enamel and dentin and oral inflammation. However, it is still a challenge that the function of natural active ingredients in currently available oral care products is not comprehensive, especially the lack of remineralization. Here, inspired by the strong biological adhesion ability of mussels and ancient oral disease plant therapy, a multifunctional strategy is proposed to construct a bioactive tooth surface to treat dental caries.

Identification of the chemical constituents in ethanolic extract by LC-MS/MS and GC-MS.

has been used to treat bronchial asthma, vitiligo, nephritis and leucopenia from ancient times in China. However, its chemical composition has not been fully understood. In this study, both LC-MS and GC-MS were used to identify the chemical composition in .

Comprehensive characterisation of phenolics from Nitraria sibirica leaf extracts by UHPLC-quadrupole-orbitrap- MS and evaluation of their anti-hypertensive activity.

Ethnopharmacological Relevance: For more than ten scores years, the leaves and fruits of Nitraria sibirica have been used as a natural remedy for indigestion, irregular manes, and hypertension in the Middle East and Central Asia, especially, are recommended for hypertension treatment in the northwest region, China.

Aim Of The Study: we aimed to support the traditional usage of N. sibirica leaves as pharmaceuticals or dietary supplements in treatment of hypertension by investigating their chemical constituents and anti-hypertensive activity.

Phenolic glycosides from leaves and their biological activities.

Seventeen phenolic glycosides were isolated from the Their structures were identified by the spectroscopic data and comparison with literatures as isovanillyl alcohol-7----glucopyranoside (), benzyl -primeveroside (), benzyl----glucopyranoside (), 1----glucopyranosyl-4-(8-hydroxyethyl)-2-methoxyphenyl (), dehydrosyringin (), trans-ferulic acid-4----glucoside (), -ferulic acid 4----glucopyranoside (), glucosyringic acid (), 1--feruloyl---glucoside (), sachaloside VII (), (3, 5, 6, 7, 9)-megastigmane-7-ene-3-hydroxy-5,6-epoxy-9----glucopyranoside(), 3-hydroxy-4,5-dimethoxybenzyl alcohol (), pinoresinol 4----glucopyranoside (), eucommin A (), isoeucommin A (), acanthoside (), liriodendrin (). All these compounds except compound were isolated from the genus for the first time. In bioactivity assays for all compounds, the compounds and were exhibited strong antioxidant activity (IC = 18.