Publications by authors named "Chillou C"

Background: Patients with ventricular tachycardia and ischemic cardiomyopathy are at high risk for adverse outcomes. Catheter ablation is commonly used when antiarrhythmic drugs do not suppress ventricular tachycardia. Whether catheter ablation is more effective than antiarrhythmic drugs as a first-line therapy in patients with ventricular tachycardia is uncertain.

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  • Robotic magnetic navigation (RMN)-guided catheter ablation (CA) technology has been effectively used for nearly 20 years in treating heart rhythm disorders, showing benefits like greater catheter stability and safety.
  • This consensus paper aims to compile current knowledge and offer guidelines on utilizing RMN-guided CA for conditions like atrial fibrillation (AF) and ventricular arrhythmias (VA).
  • The expert group reviewed literature and shared experiences to create a structured set of recommendations, addressing practical aspects of RMN use in clinical settings for optimal patient care.
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  • This study looks at how well doctors can predict sudden cardiac death after someone has a heart attack using a measurement called left ventricular ejection fraction (LVEF).
  • They combined information from over 140,000 heart attack patients to see if LVEF alone is good enough for deciding who should get a heart device called a defibrillator.
  • The results showed that LVEF didn't do a great job at predicting sudden cardiac death, which means doctors need better ways to tell who is at risk.
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Background And Aims: Prophylactic implantable cardioverter-defibrillators (ICDs) are not recommended until left ventricular ejection fraction (LVEF) has been reassessed 40 to 90 days after an acute myocardial infarction. In the current therapeutic era, the prognosis of sustained ventricular arrhythmias (VAs) occurring during this early post-infarction phase (i.e.

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Stereotactic arrythmia radioablation (STAR) is a novel, non-invasive and promising treatment option for ventricular arrythmias (VA). It has been applied in highly selected patients mainly as bail-out procedure, when (multiple) catheter-ablations, together with anti-arrhythmic drugs, were unable to control the VAs. Despite the increasing clinical use there is still limited knowledge of the acute and long-term response of normal and diseased myocardium to STAR.

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Cardiac sarcoidosis (CS) is a form of inflammatory cardiomyopathy associated with significant clinical complications such as high-degree atrioventricular block, ventricular tachycardia, and heart failure as well as sudden cardiac death. It is therefore important to provide an expert consensus statement summarizing the role of different available diagnostic tools and emphasizing the importance of a multidisciplinary approach. By integrating clinical information and the results of diagnostic tests, an accurate, validated, and timely diagnosis can be made, while alternative diagnoses can be reasonably excluded.

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  • Electrical storm (ES) is a serious condition characterized by repeated episodes of dangerous heart rhythms (ventricular arrhythmias) occurring within 24 hours, requiring medical intervention.
  • It mainly affects patients with existing heart issues or those with implantable cardioverter-defibrillators (ICDs), and it poses significant health risks despite advanced treatments.
  • The increasing number of older patients with heart conditions and ICDs suggests that the incidence of ES is likely to rise, prompting the need for comprehensive management strategies and a multi-disciplinary approach.
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Catheter ablation is nowadays considered the treatment of choice for numerous cardiac arrhythmias in different clinical scenarios. Fluoroscopy has traditionally been the primary imaging modality for catheter ablation, providing real-time visualization of catheter navigation. However, its limitations, such as inadequate soft tissue visualization and exposure to ionizing radiation, have prompted the integration of alternative imaging modalities.

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  • Heart transplantation (HT) may be a lifesaving option for patients experiencing severe refractory electrical storm (ES), a condition characterized by uncontrollable heart arrhythmias, with limited existing data on this approach.
  • A retrospective study involving 45 patients from 11 French centers revealed that 28.9% experienced in-hospital mortality, with predictors including kidney function and the need for immediate post-operative support.
  • One-year survival after surgery was reported at 68.9%, indicating that while many patients can recover and be discharged, significant risks remain, highlighting the need for larger studies to better understand patient outcomes.
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  • This study looked at how heart muscle movement, using a special test called strain echocardiography, can help understand heart problems in patients with mitral valve prolapse (MVP) and severe heart rhythms.
  • Mitral valve prolapse is when a valve in the heart doesn't work properly, and while it usually isn't serious, some people can have dangerous heart rhythms.
  • The study found that patients with severe heart rhythms had different heart muscle movement patterns, which might help doctors predict who is at risk for these dangerous heart conditions.
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To develop a suite of quality indicators (QIs) for the management of patients with ventricular arrhythmias (VA) and the prevention of sudden cardiac death (SCD). The Working Group comprised experts in heart rhythm management including Task Force members of the 2022 European Society of Cardiology (ESC) Clinical Practice Guidelines for the management of patients with VA and the prevention of SCD, members of the European Heart Rhythm Association, international experts, and a patient representative. We followed the ESC methodology for QI development, which involves (i) the identification of the key domains of care for the management of patients with VA and the prevention of SCD by constructing a conceptual framework of care, (ii) the development of candidate QIs by conducting a systematic review of the literature, (iii) the selection of the final set of QIs using a modified-Delphi method, and (iv) the evaluation of the feasibility of the developed QIs.

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Background: Pulmonary vein (PV) isolation (PVI) has become the cornerstone of atrial fibrillation (AF) ablation in patients with paroxysmal AF (PAF). PVI durability is influenced by many factors including PVs anatomy. Data regarding the influence of PVs anatomical variations on the outcomes of PAF ablation in the era of contact force-sensing ablation catheters are scarce and contradictory.

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We aim to describe the technical aspects of pace mapping (PM), as well as the two typical patterns of pacing correlation maps during ventricular tachycardia (VT) ablation. The first main pattern is focal, with a gradual and eccentric decrease of the QRS correlation from the area with the best PM correlation. This focal pattern may be associated with two clinical situations: (1) with some endocardial points showing a good correlation compared to VT morphology: true endocardial exit of VT or endocardial breakthrough of either an intramural or an epicardial circuit; (2) without any endocardial points showing a good correlation compared to VT morphology: the VT may originate from the other ventricle, but the presence of an intramural or an epicardial circuit should be considered in patients with a structural heart disease.

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Background: Catheter ablation (CA) technology development reflects the need to improve the effectiveness of atrial fibrillation (AF) treatment. Recently, the DiamondTemp Ablation (DTA) RF generator software was updated with a more responsive power ramp.

Methods: DIAMOND FASTR-AF was a prospective, single-arm, multicenter trial.

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The prevalence of both organic valvular heart disease (VHD) and cardiac arrhythmias is high in the general population, and their coexistence is common. Both VHD and arrhythmias in the elderly lead to an elevated risk of hospitalization and use of health services. However, the relationships of the two conditions is not fully understood and our understanding of their coexistence in terms of contemporary management and prognosis is still limited.

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Laser balloon (LB) has emerged as an interesting strategy for pulmonary vein isolation in paroxysmal atrial fibrillation (AF). A third-generation LB has recently been developed, allowing a continuous ablation set. We aimed to compare the results from our center's experience with second and third-generation LBs to a cohort of matched patients who had undergone radiofrequency ablation (RFA) with contact-force catheters.

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Remote magnetic navigation (RMN) is as safe and effective as manual navigation for catheter ablation of ventricular arrhythmias. This case is the first description of a soft-tip ablation catheter entrapment in the mitral valve apparatus during an RMN ablation procedure. The tight knot created by the catheter around a mitral valve chordae required surgical removal.

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  • - The study investigates how well Activated Clotting Time (ACT) measures the effectiveness of unfractionated heparin (UFH) in patients undergoing atrial fibrillation (AF) ablation, especially those on different anticoagulants like Direct Oral Anticoagulants (DOACs) versus vitamin K antagonists (VKAs).
  • - It found that patients on DOACs needed significantly higher doses of UFH and longer times to reach target ACT levels compared to those on VKAs, leading to concerns that the current ACT target may cause unnecessary overdosing of heparin in DOAC patients.
  • - The correlation between ACT and the actual anticoagulant effect (measured by anti-Xa activity) was stronger in
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Background: Atrial fibrillation (AF) leads to the development of cardiac remodeling/diastolic dysfunction and vice versa. We intended to determine whether cardiac remodeling/diastolic dysfunction is present at early stages of AF.

Methods: We studied 175 patients with paroxysmal AF, compared with 175 matched control subjects, who had available echocardiography data to investigate the association between echocardiographic variables and AF from the STANISLAS cohort.

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