Publications by authors named "Chikako Katakami"
A 61-year-old man presented with corneal perforation of 1.0 mm in diameter in his right eye caused by a metallic foreign body fragment. We used the "one-bite mini-keratoplasty" technique, which uses a cornea patch with a single host-graft-host suture to stop aqueous humor leakage.
View Article and Find Full Text PDFPurpose: To evaluate the ability of deep learning (DL) models to detect obstructive meibomian gland dysfunction (MGD) using in vivo laser confocal microscopy images.
Methods: For this study, we included 137 images from 137 individuals with obstructive MGD (mean age, 49.9 ± 17.
Article Synopsis
- The study aimed to evaluate the accuracy of two methods for measuring endothelial cell density (ECD) in patients using different types of specular microscopes.
- Three different microscopes were used to take images from each of 45 patients, comparing methods for consistency and precision.
- Results indicated high correlation (ICC > 0.9) across microscopes, but precision was limited, with the center-dot method showing mean differences in ECD measurements ranging between 42 to 57 cells/mm.
Aim: To evaluate the antifibrogenic effects of butyrate or phenylbutyrate, a chemical derivative of butyrate, in human pterygium fibroblasts.
Methods: Human pterygium fibroblasts obtained from patient pterygium tissue were treated with butyrate or phenylbutyrate for 48h. Expression of α-smooth muscle actin, collagen I, collagen III and matrix metalloproteinase-1 mRNA was measured by quantitative real-time reverse transcription polymerase chain reaction, and acetylated histone was evaluated by Western blotting.
The role of oxidative stress and inflammation in conjunctivochalasis.
Invest Ophthalmol Vis Sci
April 2010
Purpose. To investigate the status of oxidative stress and histopathologic alterations in patients with conjunctivochalasis and compare the findings with those in healthy control subjects. Methods.
View Article and Find Full Text PDFPurpose: To elucidate the status of the conjunctival inflammation in atopic keratoconjunctivitis (AKC) using laser scanning confocal microscopy and compare the relevant findings with conjunctival brush cytology in a prospective controlled study.
Methods: Twenty eyes from 20 AKC patients as well as 16 eyes from 16 age and sex matched normal subjects were studied. The subjects underwent tear film break-up time (BUT), fluorescein and Rose Bengal staining of the ocular surface, conjunctival confocal microscopy, Schirmer test, and brush cytology.
Purpose: The effects of various eye drops on corneal wound healing, particularly in the subepithelial haze area, were investigated histologically following superficial keratectomy in rabbits.
Methods: Mechanical superficial keratectomy was performed in rabbit eyes. Tranilast, betamethasone, hyaluronic acid, and diclofenac eye drops were administered after the procedure.
Purpose: To observe the clinical and histopathological changes occurring in corneas of KKAy mice, a model of type 2 diabetes, and to elucidate the possible mechanisms involved in these changes.
Methods: Corneal epithelial cell proliferation was analyzed in KKAy and age-matched non-diabetic C57BL/6J control mice using (3)H-thymidine autoradiography. Clinical examination and histopathological analysis were also conducted on both types of mice.
[Effects of various eye drops on corneal wound healing after superficial keratectomy in rabbits].
Nippon Ganka Gakkai Zasshi
March 2002
Purpose: The effects of various eye drops on corneal wound healing, particularly in the subepithelial haze area, investigated histologically following superficial keratectomy in rabbits.
Material And Methods: Mechanical superficial keratectomy was performed in rabbit eyes. Tranilast, betamethasone, hyaluronic acid and diclofenac eye drops were administered after the procedure.