Publications by authors named "Chika Shuto"
Neuromodulation of peripheral nerves with bioelectronic devices is a promising approach for treating a wide range of disorders. Wireless powering could enable long-term operation of these devices, but achieving high performance for miniaturized and deeply placed devices remains a technological challenge. We report the miniaturized integration of a wireless powering system in soft neuromodulation device (15 mm length, 2.
View Article and Find Full Text PDFAims: Thoracic spinal cord stimulation (SCS) has been shown to improve left ventricular ejection fraction (LVEF) in heart failure (HF). Nevertheless, the optimal duration (intermittent vs. continuous) of stimulation and the mechanisms of action remain unclear.
View Article and Find Full Text PDFArticle Synopsis
- Preclinical studies indicate that thoracic spinal cord stimulation (SCS) may enhance left ventricular function in patients with heart failure.
- This study was conducted to assess the safety and effectiveness of SCS as a treatment for systolic heart failure in patients with specific conditions.
- The trial involved 22 patients, revealing that SCS treatment led to significant improvements in heart function, symptoms, and overall quality of life, while no benefits were seen in patients who did not receive the treatment.
Background: Prior experimental studies show that thoracic spinal cord stimulation (SCS) improves left ventricular (LV) ejection fraction (LVEF). The mechanism of this improvement in the LV contractile function after SCS and its effects on the myocardial oxygen consumption remains unknown.
Methods And Results: We performed thoracic SCS (T1-T2 level) followed by 4 weeks of rapid ventricular pacing in 9 adult pigs with ischemic heart failure (HF) induced by myocardial infarction (MI).