Sentinel lymph node biopsy in acral melanoma: A Korean single-center experience with 107 patients (2006-2018).

Background: Sentinel lymph node biopsy (SLNB) of primary cutaneous melanoma as an important staging method has not been popularly undertaken in Korea and only a few studies with small patient numbers have been published.

Aim: We examined the clinical feasibility and overall outcomes of SLNB in acral melanoma (AM) of Korean in Kyungpook National University Hospital (KNUH) over the past 13 years.

Methods: SLNB in AM patients during 2006-2018 were analyzed retrospectively for sentinel lymph node (SLN) harvesting rate, positivity rate, positivity-relevant overall survival (OS) and disease-free survival (DFS), and its side effects.

Usefulness of home-use microneedle devices in the treatment of pattern hair loss.

Background: Microneedle devices have been used to reduce scarring and wrinkling as well as for the treatment of pattern hair loss.

Aims: Here, we investigated the efficacy and safety of a newly developed home-use microneedle device for the treatment of pattern hair loss.

Methods: Twenty-nine patients were assigned into three groups based on block randomization: home-use microneedle device only, a combination of home-use microneedle device and 5% minoxidil solution and 5% minoxidil topical solution only.

Effect of a sphingolipid-mimetic compound on the promotion of hair growth: A randomized, double-blind, placebo-controlled clinical trial.

Background: Pattern hair loss is a very common skin disorder, but more therapeutic modalities for hair growth are still required.

Objective: We investigated the effect of a newly synthesized sphingolipid-mimetic compound (pseudo-ceramide: bis-oleamide isopropyl alcohol [BOI]) on the promotion of hair growth for patients with mild pattern hair loss.

Methods: A total of 58 patients with mild pattern hair loss participated in this clinical trial.