Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors.

Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China.

Materials And Methods: To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents from Physalis minima.

Results: It was demonstrated that the ethyl acetate extract of P.

An Unusual Stress Metabolite from a Hydrothermal Vent Fungus Aspergillus sp. WU 243 Induced by Cobalt.

A novel hybrid polyketide-terpenoid, aspergstressin (1), possessing a unique fused polycyclic structure, was induced from culture broth of strain Aspergillus sp. WU 243 by cobalt ion stimulation. The strain was isolated from the digestive gland of Xenograpsus testudinatus, a unique type of crab which dwells in the Kueishantao hydrothermal vents off Taiwan.