Publications by authors named "Chihiro Yoshikawa"

Article Synopsis
  • The study explored how the COVID-19 pandemic affected the diagnosis and treatment of colorectal cancer (CRC) by comparing patient data before and during the pandemic.* -
  • Findings showed a significant decrease in positive fecal occult blood tests and patients took longer to seek medical help for symptoms during the pandemic, even though the stage of cancer remained unchanged.* -
  • Despite patients being hesitant to seek treatment, healthcare practitioners' behavior stayed consistent, resulting in no significant differences in overall survival or recurrence-free survival rates.*
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Article Synopsis
  • - A 31-year-old man experienced epigastric pain and was diagnosed with acute peritonitis linked to an ectopic pancreas located in a jejunal duplication, along with intestinal malrotation.
  • - The patient underwent a surgical procedure that involved partial resection of the jejunum and Ladd's procedure to address the issue.
  • - Histopathological analysis confirmed the presence of ectopic pancreatitis, emphasizing the need for surgery for both treatment and diagnosis in such complex cases.
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Background: Splenic artery aneurysms usually rupture into the free peritoneal space and rarely into the gastrointestinal tract. We report the case of a patient with a giant splenic artery aneurysm that ruptured in to the stomach with hemorrhagic shock and was successfully treated with emergency surgery.

Case Presentation: A 59-year-old man presented to the emergency department with chest pain and syncope.

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A 70-year-old man underwent surveillance colonoscopy following surgery for occlusive sigmoid colon cancer. The procedure revealed nine sessile serrated lesions (SSLs), including three inverted lesions. Endoscopic and surgical resections were performed.

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The first case is a 62-year-old female who complained of painful left axillary lymph node swelling. Six months later, a CT scan revealed multiple lung nodules. Biopsies of the axillary lymph node and lung showed metastatic carcinoma from breast cancer.

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This case was observed in a man in his 70s. Although symptomatic treatment was performed for epigastralgia, endoscopic examination revealed a type 3 tumor on the fornix of the stomach to the lesser curvature of the body just above the esophagogastric junction, and the patient was diagnosed with moderately differentiated tubular adenocarcinoma(cT4bN3aM0, cStage ⅣA). As esophageal and diaphragmatic invasion was suspected based on CT findings, S-1 plus CDDP was started as preoperative chemotherapy.

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A 66-year-old woman underwent distal gastrectomy because of gastric cancer(stage ⅠB)and received no adjuvant chemotherapy. Eight years after the operation, computed tomography showed a small nodule in the right breast. Mammography did not reveal any abnormalities.

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A 76-year-old female underwent breast-conserving surgery of the right breast and sentinel lymph node biopsy for primary breast cancer. Three years later, mammography and ultrasonography showed a small nodule in the right breast. There was nothing abnormal in the left breast.

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Background: Valgus-impacted femoral neck fractures treated with internal fixation occasionally result in unsatisfactory postoperative locomotive function, partially due to muscle shortening and a decrease in the moment arm. This study quantifies the degree of diminished abduction strength both clinically and biomechanically.

Methods: Fifteen patients were enrolled in this study.

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Background: The current study focuses on the comparison of postoperative muscular strength around the hip joint of patients with femoral intertrochanteric fractures treated either by cephalo-medullary (CM) nailing or a new bipolar hip prosthesis (BHP), an especially attached device to secure displaced greater trochanteric fragment.

Methods: Twenty patients treated with CM nailing were age- and sex- matched with a control group of 20 patients treated with BHP. Maximum isometric forces at the bilateral hip joint were measured during the follow up period.

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Most growth factors stimulate myoblast proliferation and prevent differentiation, whereas insulin-like growth factors (IGFs) promote myoblast differentiation through the phosphatidylinositol 3-kinase (PI3K) pathway. Subtilisin-like proprotein convertases (SPCs) are involved in cell growth and differentiation via activation of pro-growth factors. However, the role of SPCs in myogenesis remains poorly understood.

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