Publications by authors named "Chihiro Nakashita"
Background: This study aimed to examine the impact of dietary compositions and patterns on nonalcoholic fatty liver disease (NAFLD) morbidity in Japanese men.
Methods: We conducted a cross-sectional study of 281 individuals who underwent comprehensive medical examinations during health screening. Dietary intake was assessed using a semi-quantitative food frequency questionnaire, and factor analysis was performed to detect dietary patterns.
Objective: We conducted an analysis using the Quick Environmental Exposure Sensitivity Inventory to examine the correlation between multiple chemical sensitivity (MCS) and personality traits by using temperament and character inventory, and environmental exposures.
Methods: An anonymous questionnaire was distributed to 667 employees working at an IT manufacturing plant in Japan. Variables including chemically sensitive population (CSP), personality, and environmental chemical exposure were individually evaluated using U-test, chi-squared test, and correlation analyses.
Objectives: The objectives of this study were to assess the possibility of utilization of genetic testing and to determine the effect of participant characteristics on genetic testing awareness in Japanese workers.
Methods: The subjects of this study consisted of 998 workers from two companies located in Kyusyu, Japan, from June to July, 2014. We examined the participant characteristics and genetic testing awareness using paper questionnaires.
[Application of Metabolomics to Multiple Chemical Sensitivity Research].
Nihon Eiseigaku Zasshi
October 2016
Article Synopsis
- Multiple Chemical Sensitivity (MCS) is a chronic condition with vague symptoms linked to low-level chemical exposure, making diagnosis tricky due to a lack of standard definitions and assessment methods.
- Advances in mass spectrometry and metabolomics have enhanced our ability to analyze biological samples for specific molecules, paving the way for new diagnostic tools.
- In a study comparing 9 MCS patients to 9 controls, researchers found altered levels of several metabolites, including increased hexanoic and pelargonic acids and decreased acetylcarnitine in MCS patients, hinting at potential biomarkers for the condition.
Objectives: We sought to identify associations between aldehyde dehydrogenase 2 (ALDH2), alcohol consumption, and hypertension in Japanese men.
Methods: The study participants were 1,225 male Japanese workers. We collected lifestyle information, body measurements, blood biochemical parameters, blood pressure measurements, and ALDH2 genotyping data during medical examinations conducted between March 2004 and January 2005 at a work facility and an affiliated company.