Publications by authors named "Chih-Hsuan Luan"
Article Synopsis
- The study investigates the effectiveness of direct-acting antiviral agents (DAAs) in treating Taiwanese patients with chronic hepatitis C (HCV) who have also experienced hepatocellular carcinoma (HCC).
- A total of 94 patients were analyzed after receiving DAA treatment, with findings showing a high rate of sustained virological response (95.7%), but a significant recurrence of HCC at 54.3%.
- Key risk factors for HCC recurrence included prior HCC recurrence, lack of sustained virological response, elevated post-treatment alpha-fetoprotein levels, and specific characteristics of liver lesions.
Background: The treatment of chronic hepatitis C (CHC) infection underwent a significant transformation with the introduction of all-oral direct-acting anti-virals (DAAs). These medications offered a high success rate in treatment, shorter duration, good tolerability, and expanded treatment options. However, a residual risk of hepatocellular carcinoma (HCC) development remained for a few patients even after achieving sustained virological response (SVR).
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