Prognostic factors for mortality in patients hospitalized with influenza complications, in Taiwan.

Background: This study aims to assess factors associated with fatal hospitalized influenza with complications in Taiwan.

Methods: We identified reports of complications and illness onset in patients hospitalized with influenza between week 26, 2009 and week 25, 2012 from the National Notifiable Disease Surveillance System. We used a multivariate logistic regression model to evaluate covariates that can be associated with in-hospital mortality.

Telephone monitoring of adverse events during an MF59®-adjuvanted H5N1 influenza vaccination campaign in Taiwan.

This study was conducted to explore a telephone-based approach for identifying and quantifying the occurrence of adverse events following immunization (AEFIs) during an MF59®-adjuvanted H5N1 vaccination program in Taiwan. From March to August 2011, each H5N1 vaccine recipient who voluntarily registered as participants within 72 h of vaccination was phone interviewed at postvaccination 7-10 and 21-24 d. Among the 292 participants, 270 and 263 interviews were completed at 7-10 and 21-24 d.

Application of the parallel line assay to assessment of biosimilar products based on binary endpoints.

Biological drug products are therapeutic moieties manufactured by a living system or organisms. These are important life-saving drug products for patients with unmet medical needs. Because of expensive cost, only a few patients have access to life-saving biological products.