Bioactive compounds for neuropathic pain: An update on preclinical studies and future perspectives.

Among different types of chronic pain, neuropathic pain (NP), arising from damage to the nervous system, including peripheral fibers and central neurons, is notoriously difficult to treat and affects 7-10% of the general population. Currently available treatment options for NP are limited and opioid analgesics have severe side effects and can result in opioid use disorder. Recent studies have exhibited the role of dietary bioactive compounds in the mitigation of NP.

Effects of short-term acupuncture treatment on occlusal force and mandibular movement in patients with deep-bite malocclusion.

Background/purpose: Acupuncture is well known to be effective for pain relief and muscle relaxation, and hence it is feasible that acupuncture treatment could change the occlusal forces and mandibular movements in subjects with deep-bite malocclusion. The purpose of this research was to determine the distribution of occlusal force and the border movement of the mandible in patients with deep-bite malocclusion before and after acupuncture treatment.

Materials And Methods: This study involved 17 volunteers with deep-bite malocclusion and aged 20-30 years.