Publications by authors named "Chih Wei Yang"

Aim: This scoping review aimed to identify potential variables influencing healthcare provider's perceived workload or stress when performing resuscitation on patients in cardiac arrest.

Methods: We searched Medline, EMBASE, PsycINFO, Cochrane, and Allied Health Literature (CINAHL) to identify studies published prior to February 1, 2024. We used a PECO format for this review: the population were healthcare providers performing resuscitation during simulated or real cardiac arrest; the exposure was the presence of any factor that could impact perceived workload or stress; and the comparator was the absence of any specific factor.

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Leptospirosis, a re-emerging zoonotic disease caused by spp., poses significant global health and veterinary challenges. Long-term colonization of renal tubules by in asymptomatic hosts highlights the need for sensitive detection methods.

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Upper gastrointestinal angiodysplasia (UGIA) is a unique mucosal vascular lesion that causes acute or recurrent gastrointestinal bleeding. Despite the increasing incidence of UGIA, the risk factors for bleeding in this condition remain unclear. We investigated the predictors of active and recurrent bleeding among patients with UGIA.

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Background: Acute kidney injury (AKI) is associated with increased in-hospital and short-term hypoglycemia risk. However, the impact of non-recovery of renal function before discharge on hypoglycemia risk in AKI survivors after discharge have not been well studied. We aim to analyze the association between non-recovery of AKI and hypoglycemia, hyperglycemia crisis risk, to identify additional risk factors for hypoglycemia, and to examine the impact of AKI non-recovery on HbA1c variability.

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Background: Impostor syndrome and burnout are highly prevalent among medical students and trainees, significantly impacting their mental health and professional development. The advent of online educational interventions provides a promising solution, offering accessibility and flexibility to tackle these issues. This systematic review aims to evaluate the effectiveness of online educational interventions in alleviating impostor syndrome and burnout among medical learners.

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Article Synopsis
  • The eighth annual summary from the International Liaison Committee on Resuscitation (ILCOR) focuses on the latest findings in cardiopulmonary resuscitation (CPR) and emergency cardiovascular care, building on a comprehensive review from 2020.
  • This summary is based on the evaluation of recent resuscitation evidence by experts from six different ILCOR task forces, who utilized specific criteria to assess the quality of evidence and reached consensus treatment recommendations.
  • The document also identifies key areas where more research is needed, sharing insights into the task forces’ discussions through sections like Justification and Evidence-to-Decision Framework Highlights.
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This is the eighth annual summary of the International Liaison Committee on Resuscitation International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations; a more comprehensive review was done in 2020. This latest summary addresses the most recent published resuscitation evidence reviewed by the International Liaison Committee on Resuscitation task force science experts. Members from 6 International Liaison Committee on Resuscitation task forces have assessed, discussed, and debated the quality of the evidence, using Grading of Recommendations Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations.

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Introduction: Evidence suggests a survival benefit from resuming angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor blockers (ARB) post acute kidney injury (AKI) compared to nonuse; however, the optimal timing and its impact on outcomes are unclear. The risks of earlier resumption, such as recurrent AKI or hyperkalemia, remain unexplored.

Methods: Using multiinstitutional electronic health records, we analyzed the relationship between 3 ACEI or ARB (ACEI/ARB) resumption timelines post-AKI (prior to discharge, 0-3 months, and 4-6 months postdischarge) and outcomes including all-cause mortality, major adverse cardiac and cerebrovascular events (MACCEs), dialysis initiation or end-stage renal disease (ESRD), severe hyperkalemia, and recurrent AKI with hospitalization.

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Study Objective: Cardiopulmonary resuscitation (CPR) is critical for out-of-hospital cardiac arrest patients but is prone to rapid changes and errors. Effective teamwork and leadership are essential for high-quality CPR. We aimed to introduce the Airway-Circulation-Leadership-Support (A-C-L-S) teamwork model in the emergency department (ED) to address these challenges.

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  • Clinical shadowing allows preclinical medical students to observe doctors, helping them understand important clinical competencies through reflective writings.
  • A thematic analysis was conducted on 155 reflective writings from students at National Taiwan University, revealing that patient care was the most frequently noted competency, followed by systems-based practice and medical knowledge.
  • The majority of reflections were categorized as concrete experiences, indicating that students primarily learned through direct observation rather than through abstract thinking or reflection.
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  • - Oropharyngeal dysphagia is common in neurological patients and can lead to serious issues like aspiration pneumonia, often requiring long-term feeding through methods like NGT or PEG.
  • - A study from 2015 to 2022 examined pneumonia risk in these patients, finding that those with a history of pneumonia or on enteral feeding had a higher risk, but PEG users had a significantly lower risk of hospitalization due to pneumonia compared to NGT users.
  • - The study suggests using Modified Flexible Endoscopic Evaluation of Swallowing (mFEES) for screening dysphagia and recommends PEG feeding as the safer option for reducing pneumonia risks in patients with swallowing difficulties.
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  • Collaborative learning, especially through small group teaching, has become increasingly relevant in medical education, particularly after the shift to online formats due to the Covid-19 pandemic.
  • This study focused on 263 medical students to explore the connection between group metacognition and teamwork satisfaction after participating in online small group tutorials.
  • Results indicated that most dimensions of group metacognition (knowledge of cognition, planning, and evaluating) positively influenced teamwork satisfaction, emphasizing the importance of these skills in enhancing collaborative online learning experiences.
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The effects of replacing 5-25% of wheat flour (WF) with Taiwanese cocoa bean shells (CBSs) on the physicochemical, antioxidant, starch digestion, and sensory properties of the bread were studied. The lead (0.18) and cadmium (0.

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Background: Chest compression at a rate of 100-120 compressions per minute (cpm) during cardiopulmonary resuscitation (CPR) is associated with the highest survival rates. Performing compressions at a faster rate may exhaust the rescuers.

Objectives: To compare a new cue of 'two compressions per second' to the traditional cue of '100-120 compressions per minute' on compression rate in CPR training.

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Background: Data monitoring and surveillance systems are the cornerstone for governance and regulation, planning, and policy development for chronic disease care. Our study aims to evaluate health systems capacity for data monitoring and surveillance for kidney care.

Methods: We leveraged data from the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA), an international survey of stakeholders (clinicians, policymakers and patient advocates) from 167 countries conducted between July and September 2022.

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  • Emergency medical services (EMS) face challenges when implementing new practices, making effective strategies crucial for success.
  • A systematic review of 371 studies identified 19 relevant articles that highlight 46 factors influencing EMS implementation, categorized into ten themes.
  • The study proposes a 10-theme framework emphasizing key elements like training, communication, and practitioner attitudes for better EMS practice integration.
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  • * Conducted as a cluster randomised controlled trial in Taipei City, Taiwan, with participation from advanced life support ambulance teams between July 2020 and June 2023, excluding a temporary halt due to the covid-19 pandemic.
  • * Results showed no significant difference in survival rates; 10.7% of intraosseous patients and 10.3% of intravenous patients were discharged alive, with similar outcomes for return of spontaneous circulation and neurological recovery.
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: Patients with cirrhosis are susceptible to sepsis and septic shock. Cirrhotic patients also have increased capillary permeability and are prone to developing volume overload. Patients with septic shock may have an enhanced pulmonary vascular permeability index (PVPI) and extravascular lung water index (EVLWI), both of which are associated with an unfavorable prognosis.

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  • The KDIGO Clinical Practice Guideline for Chronic Kidney Disease (CKD) updates the 2012 guideline, reflecting a comprehensive review of new evidence and advancements in treatment but does not apply to dialysis patients or those with transplants.
  • The guideline addresses evaluation, risk assessment, and management strategies to slow CKD progression, using a systematic approach to assess the quality and strength of recommendations.
  • It includes practice points, infographics, and highlights future research needs, aiming to serve a wide audience and consider implications for healthcare policies and payment systems.*
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Acute kidney injury is a common and complex complication that has high morality and the risk for chronic kidney disease among survivors. The accuracy of current AKI biomarkers can be affected by water retention and diuretics. Therefore, we aimed to identify a urinary non-recovery marker of acute kidney injury in patients with acute decompensated heart failure.

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Background: Competency-based medical education (CBME) is an outcomes-oriented approach focused on developing competencies that translate into clinical practice. Entrustable professional activities (EPAs) bridge competency assessment and clinical performance by delineating essential day-to-day activities that can be entrusted to trainees. EPAs have been widely adopted internationally, but not yet implemented for medical radiation professionals in Taiwan.

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Background: Perturbation of gut microbiota has been linked to chronic kidney disease (CKD), which was correlated with a sophisticated milieu of metabolic and immune dysregulation.

Methods: To clarify the underlying host-microbe interaction in CKD, we performed multi-omics measurements, including systems-level gut microbiome, targeted serum metabolome and deep immunotyping, in a cohort of patients and non-CKD controls.

Results: Our analyses on functional profiles of the gut microbiome showed a decrease in the diversity and abundance of carbohydrate-active enzyme (CAZyme) genes but an increase in the abundance of antibiotic resistance, nitrogen cycling enzyme and virulence factor genes in CKD.

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This study aimed to develop aptamers targeting LipL32, a most abundant lipoprotein in pathogenic Leptospira, to hinder bacterial invasion. The objectives were to identify high-affinity aptamers through SELEX and evaluate their specificity and inhibitory effects. SELEX was employed to generate LipL32 aptamers (L32APs) over 15 rounds of selection.

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Individuals, societies, and the environment are affected by neglected and emerging diseases. These diseases result in a variety of severe outcomes, including permanent disabilities, chronic diseases such as chronic kidney disease, and even mortality. Consequences include high health care expenditures, loss of means of support, social stigma, and social exclusion.

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