Directed self-assembly of Ag-deposited MoS quantum dots for colorimetric, fluorescent and fluorescence-lifetime sensing of alkaline phosphatase.

We developed a triple-readout probe for colorimetric, fluorescent, and fluorescence-lifetime sensing of alkaline phosphatase (ALP) through the hydrolyzed ascorbic acid phosphate (AAP)-mediated formation of silver nanoparticles (AgNPs) on Ag-deposited MoS quantum dots (QDs). Ag ions were self-assembled on a monolayer MoS QD surface through the formation of Ag-S bonds. When ALP hydrolyzed AAP in an alkaline buffer, the resultant ascorbic acid (AA) triggered the reduction of the bound Ag ions into AgNPs on the MoS QD surface.

Using Healthcare IC Cards to manage the drug doses of chronic disease patients.

In Taiwan's medical system, the Healthcare IC Card is used as form of secure data storage. This research applies the Healthcare IC Card to record the chronic disease patient's recent drug doses, diagnoses and prescriptions. With the Hospital Information System, this research combines the diagnosis records stored in the Healthcare IC Card to establish a platform which could simulate the procedures of a doctor in examining a patient and checking the circumstances of the patient's repetitive drug doses and drugs interactions.