Publications by authors named "Chien-Lung Huang"

Potent P2Y receptor antagonists have been used widely for patients undergoing percutaneous coronary intervention with different results. Benefits from different regimens various between trials. Randomized controlled trials (RCTs) have restrictive inclusion and exclusion criteria; thus, they may limit the generalizability of the findings to a broader population.

View Article and Find Full Text PDF

Background: Health-related quality of life (HRQoL) is an important indicator of patient's satisfaction about their disease course. Many factors are influential to life quality, such as dignity and resilience. Dignity is mostly explored in populations with cancer, but the understanding of dignity and its relationship with resilience and HRQoL is limited.

View Article and Find Full Text PDF

Magnetic order in most materials occurs when magnetic ions with finite moments arrange in a particular pattern below the ordering temperature. Intriguingly, if the crystal electric field (CEF) effect results in a spin-singlet ground state, a magnetic order can still occur due to the exchange interactions between neighboring ions admixing the excited CEF levels. The magnetic excitations in such a state are spin excitons generally dispersionless in reciprocal space.

View Article and Find Full Text PDF
Article Synopsis
  • Propafenone, a class IC antiarrhythmic drug, is a standard treatment for paroxysmal atrial fibrillation (AF) in Taiwan, and this study investigates the effectiveness and safety of its generic version (Rhynorm) compared to the brand name (Rytmonorm).
  • The study involved 76 patients with AF, using a wearable ECG to track AF episodes over 24 weeks, focusing on the frequency of significant AF occurrences and any adverse effects.
  • The results showed that Rhynorm is as effective and safe as Rytmonorm for treating AF, with no significant differences between the two groups, confirming Rhynorm's noninferiority.
View Article and Find Full Text PDF

Peripheral artery disease (PAD) imposes a heavy burden of major adverse cardiovascular events that are associated with considerable mortality and morbidity, and major adverse limb events (e.g., thrombectomy, revascularization, amputation) that can substantially impact patients' daily functioning and quality of life.

View Article and Find Full Text PDF

Background: Proximal protection devices, such as the Mo.Ma system provides better neurological outcomes than the distal filter system in the carotid artery stenting (CAS) procedure. This study first evaluated the safety and efficacy of the Mo.

View Article and Find Full Text PDF
Article Synopsis
  • Pharmacogenetics could explain the "East Asian paradox," where East Asian ACS patients show higher platelet reactivity on clopidogrel despite lower ischemic risk compared to Western patients.
  • The study involved genotyping 102 Taiwanese ACS patients to assess the effects of switching from clopidogrel to low-dose prasugrel on platelet activity and clinical outcomes.
  • Results indicated that the switch significantly lowered platelet reactivity in both extensive and reduced metabolizers, particularly reducing high on-treatment platelet reactivity in reduced metabolizers, without increasing bleeding risks.
View Article and Find Full Text PDF

Pulmonary embolism (PE) is a potential life-threatening condition and risk-adapted diagnostic and therapeutic management conveys a favorable outcome. For patients at high risk for early complications and mortality, prompt exclusion or confirmation of PE by imaging is the key step to initiate and facilitate reperfusion treatment. Among patients with hemodynamic instability, systemic thrombolysis improves survival, whereas surgical embolectomy or percutaneous intervention are alternatives in experienced hands in scenarios where systemic thrombolysis is not the best preferred thromboreduction measure.

View Article and Find Full Text PDF

Background: Previous studies have shown that the use of fractional flow reserve (FFR) in addition to angiography significantly reduced the rate of all major adverse cardiovascular events (MACE). However, this practice has not been widely accepted and limited outcome data exist about FFR-guided percutaneous coronary intervention (PCI) in Taiwan. The aim of the present study was to evaluate the possible impact of FFR-guided PCI in coronary stenoses of intermediate severity.

View Article and Find Full Text PDF

The microscopic mechanism governing the zero-resistance flow of current in some iron-based, high-temperature superconducting materials is not well understood up to now. A central issue concerning the investigation of these materials is their superconducting gap symmetry and structure. Here we present a combined study of low-temperature specific heat and scanning tunnelling microscopy measurements on single crystalline FeSe.

View Article and Find Full Text PDF

Unlabelled: Deep vein thrombosis (DVT) is a potentially catastrophic condition because thrombosis, left untreated, can result in detrimental pulmonary embolism. Yet in the absence of thrombosis, anticoagulation increases the risk of bleeding. In the existing literature, knowledge about the epidemiology of DVT is primarily based on investigations among Caucasian populations.

View Article and Find Full Text PDF

Background: Although radial access for drug-eluting stent (DES) combined with rotational atherectomy (RA) in patients with calcified coronary lesions may be associated with a lower risk of major bleeding complications and obtain favorable clinical results compared with femoral access, the long-term outcome data of this approach were limited in contemporary DES era.

Methods & Results: This retrospective study sought to compare in-hospital and long-term outcomes for patients undergoing RA via the transradial (TR) and transfemoral (TF) route in 126 consecutive patients (59 radial, 67 femoral) from 2009 to 2014. TR RA procedures were performed in 44/62 (71%) by the three TR operators, compared with 15/64 (23%) by the four TF operators in the present study.

View Article and Find Full Text PDF