Publications by authors named "Chien-Fu Cheng"

Article Synopsis
  • - The study focuses on a mosquito species from Asia that was introduced to Africa in the 2000s, which can transmit various diseases and has become a nuisance in places like the Democratic Republic of Sao Tome and Principe from 2000 to 2016.
  • - Researchers collected adult mosquitoes and their larvae from 15 locations using different trapping methods, identifying four new mosquito species in the process and detailing the habitat preferences of the larvae, particularly in artificial containers like tires.
  • - Genetic analysis indicated low diversity within the invasive mosquito populations, which are known to be involved in disease transmission, highlighting the importance of monitoring and controlling this species for public health.
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Article Synopsis
  • Significant progress has been made in reducing malaria cases in São Tomé and Príncipe (STP) through vector control and case management, leading to this study assessing genetic diversity and treatment outcomes of malaria infections from 2010 to 2016.
  • Researchers sequenced specific genes related to the malaria parasite and drug resistance in 118 blood samples and analyzed treatment outcomes for 7482 cases, utilizing regression models to identify factors affecting parasite density and treatment failures.
  • The study found notable genetic changes in malaria strains within STP, including shifts in predominant alleles and a threefold decrease in average parasite density, while highlighting that younger patients and those treated with quinine were more likely to experience treatment failures.
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Background: Vector control is a key component of malaria prevention. Two major vector control strategies have been implemented in São Tomé and Príncipe (STP), indoor residual spraying (IRS) and outdoor larval control using Bacillus thuringiensis israelensis (Bti). This study evaluated post-intervention effects of control strategies on vector population density, composition, and knockdown resistance mutation, and their implications for malaria epidemiology in STP.

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Dengue fever has become a worldwide public health concern, threatening an estimated 40% of the world's population. However, most resources and attention are still focused on malaria, while dengue statuses are poorly recognized in many African countries. In this serological survey, dengue virus (DENV) transmission was demonstrated by using serum samples collected from 78 pregnant women in the Democratic Republic of Sao Tome and Principe (DRSTP) during 2003 to 2004.

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