A 71-year-old male experienced anaphylactic shock and was found to be resistant to adrenaline due to his beta-blocker medication, requiring glucagon to stabilize him.
The patient also developed acute coronary syndrome, leading to the identification of two contributing mechanisms of Kounis syndrome: adrenaline-induced coronary spasm and an imbalance between oxygen supply and demand triggered by the allergic reaction.
The patient’s beta-blocker treatment was stopped as his heart function remained stable, highlighting the need for careful reconsideration of using beta-blockers after severe allergic events in myocardial infarction recovery.