Effectiveness and Sustainability of Education about Incident Reporting at a University Hospital in Japan.

Objectives: The aim of this study was to evaluate the effectiveness and sustainability of educational interventions to encourage incident reporting.

Methods: This was a quasi-experimental design. The study involved nurses working in two gastroenterology surgical wards at Fukuoka University Hospital, Japan.

Production of hydroxlated flavonoids with cytochrome P450 BM3 variant F87V and their antioxidative activities.

A variant of P450 BM3 with an F87V substitution [P450 BM3 (F87V)] is a substrate-promiscuous cytochrome P450 monooxygenase. We investigated the bioconversion of various flavonoids (favanones, chalcone, and isoflavone) by using recombinant Escherichia coli cells, which expressed the gene coding for P450 BM3 (F87V), to give their corresponding hydroxylated products. Potent antioxidative activities were observed in some of the products.