Publications by authors named "Chieh-Yin Wu"

Article Synopsis
  • This study explored how Mycobacterium kansasii, which causes lung disease, may be transmitted through environmental sources, particularly water, by examining patients in Taiwan from 2015-2017.
  • Researchers analyzed sputum samples and used advanced methods to assess the genetic similarities of M. kansasii strains.
  • The results showed that individuals living near two specific water purification plants were at a higher risk for infections, emphasizing the need for more research on environmental factors linked to this disease.
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Few literatures discussed the relationship of glycemic control and body mass index (BMI) with the risk of pyogenic liver abscess. We conducted a population-based cohort study using participants of a community-based health screening program in Taiwan from 2005 to 2008 (n = 125,865). Information on fasting plasma glucose (FPG), BMI, and other potential risk factors of liver abscess were collected at baseline.

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Background: Mounting data have revealed that body mass index (BMI) is inversely associated with risk of active tuberculosis. The inverse association presents a "paradox" with regard to diabetes, because obesity is a major determinant of diabetes, and diabetes is a well-known risk factor for tuberculosis.

Methods: We conducted 2 population-based cohort studies involving 167392 participants.

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Article Synopsis
  • The post-2015 End TB Strategy aims to cut tuberculosis incidence by 50% and mortality by 75% by 2025, focusing on strategies in China, India, and South Africa to achieve these goals.
  • Researchers assessed various intervention scenarios and their costs, finding that expanding tuberculosis services could lead to significant health improvements and even cost savings in India and China, despite high initial funding needs.
  • Overall, the expansion of tuberculosis services appears to be cost-effective, offering substantial health benefits; however, further research is needed to identify the best intervention strategies for each country.
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Background: The post-2015 End TB Strategy proposes targets of 50% reduction in tuberculosis incidence and 75% reduction in mortality from tuberculosis by 2025. We aimed to assess whether these targets are feasible in three high-burden countries with contrasting epidemiology and previous programmatic achievements.

Methods: 11 independently developed mathematical models of tuberculosis transmission projected the epidemiological impact of currently available tuberculosis interventions for prevention, diagnosis, and treatment in China, India, and South Africa.

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