Publications by authors named "Chieh Cheng"

Article Synopsis
  • Taiwan effectively managed to control COVID-19 with a remarkable 253 days of no local transmission before experiencing outbreaks due to variants, despite low vaccination rates.
  • The study compared Taiwan's rapid border closure and non-pharmaceutical interventions to other countries, finding a significant difference in response times and strategies.
  • Key factors in Taiwan's success included quick responses, effective contact tracing, community cooperation, and the implementation of multiple preventive measures without strict lockdowns.
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Article Synopsis
  • Mathematical models can predict epidemic trends, but few studies on COVID-19 have included behaviors like mask wearing and vaccination, crucial for controlling the pandemic.
  • New ARIMA models were used to forecast COVID-19 case growth in Canada, France, Italy, and Israel from January 2021 to March 2022, with prediction accuracy evaluated through RMSE and AICc.
  • Results showed that protective behaviors and vaccination efforts, especially booster shots, significantly lowered COVID-19 case growth rates, highlighting their importance during different virus variants' prevalence.
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Aims: To determine factors associated with poor sleep quality among patients with pre-dialysis chronic kidney disease.

Design: This is a systematic review study guided by Preferred Reporting Items for Systematic Reviews and Meta-Analyses statements and checklist.

Data Sources: Empirical evidence was sought in major electronic databases, including Embase, MEDLINE, CINAHL and Airiti library from March to September 2022.

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  • The study focused on the effects of mitochondrial DNA changes and respiratory issues in gastric adenocarcinoma (GAC) using gastric cancer cell lines and clinical samples.
  • Researchers examined mtDNA copy numbers from 131 samples, including both cancerous and normal gastric tissues, finding a significant decrease in mtDNA in GAC samples compared to non-cancerous ones.
  • Mitochondrial dysfunction was induced in the AGS cell line by knocking down a key mitochondrial factor (TFAM), leading to altered protein expressions linked to metabolism and potentially poorer patient outcomes based on lower mtDNA levels and mutations found in tumor samples.
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In recent years there has been considerable research on body awareness, which is believed to arise from interoceptive and from exteroceptive signals. In addition, body awareness may be related to empathetic disposition during social interaction. In this paper we assess the psychometric properties of the Italian version of the Scale of Body Connection (SBC).

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Objective: Emerging evidence suggests that gut microbiome composition alterations affect neurodegeneration through neuroinflammation in the pathogenesis of Parkinson's disease (PD). Here, we evaluate gut microbiota alterations and host cytokine responses in a population of Taiwanese patients with PD.

Methods: Fecal microbiota communities from 80 patients with PD and 77 age and gender-matched controls were assessed by sequencing the V3-V4 region of the 16S ribosomal RNA gene.

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Objective: To examine differences in the functional recovery trajectories between younger and older adults with mild-moderate traumatic brain injury (TBI) in the first year postinjury as well as health-related quality of life.

Design: Observational cohort.

Setting: Level one trauma centre in the State of Washington.

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Mutations in the phosphodiesterase 8B gene (PDE8B) were recently linked to autosomal-dominant striatal degeneration clinically presenting as slowly progressive parkinsonism. PDE8B degrades cyclic adenosine monophosphate (cAMP), a second messenger involved in dopamine signaling. Dopamine deficiency is the pathognomonic feature of Parkinson's disease (PD).

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A flexible and miniaturized metal semiconductor metal (MSM) biomolecular photodetector was developed as the core photocurrent system through chemiluminescence for hydrogen peroxide sensing. The flexible photocurrent sensing system was manufactured on a 30-µm-thick crystalline silicon chip by chemical etching process, which produced a flexible silicon chip. A surface texturization design on the flexible device enhanced the light-trapping effect and minimized reflectivity losses from the incident light.

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Peptide-based supramolecular hydrogels have been comprehensively investigated in biomaterial applications because of their unique bioactivity, biofunctionality, and biocompatible features. However, the presence of organic building blocks in peptide-based hydrogels often results in low mechanical stability. To expand their practical use and range of applications, it is necessary to develop the tool kit available to prepare bioinspired, peptide-based supramolecular hydrogels with improved mechanical stability.

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The objective of this study was to review the prevalence and prognostic impact of pretreatment thrombocytosis in patients with oral squamous cell carcinoma (OSCC). Medical records of 253 patients with OSCC were retrospectively reviewed. The relationship between the platelet count, TNM stage, histologic differentiation, recurrence rate, metastasis, and survival were analyzed.

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