Publications by authors named "Chie Uekura"

Article Synopsis
  • Gastric cancer often shows decreased levels of mucin 6 (MUC6), but its role in the disease's development is not well understood.
  • Researchers created special mice models to study how the absence of MUC6 leads to gastric issues, including inflammation and cancer, exploring various biological techniques and analyses.
  • The study found that MUC6 loss triggers specific stress responses and alters sugar molecule patterns in tumors, suggesting new ways to target treatment through therapies involving mannose-rich glycans.
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Background And Aims: Although is the most important bacterial carcinogen in gastric cancer (GC), GC can emerge even after eradication. Studies suggest that various constituents of the gastric microbiome may influence GC development, but the role of individual pathogens is unclear.

Methods: Human gastric mucosal samples were analyzed by 16SrRNA sequencing to investigate microbiome composition and its association with clinical parameters, including GC risk.

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Background: Olympus Corporation has developed texture and color enhancement imaging (TXI) as a novel image-enhancing endoscopic technique.

Aim: To investigate the effectiveness of TXI in identifying colorectal adenomas using magnifying observation.

Methods: Colorectal adenomas were observed by magnified endoscopy using white light imaging (WLI), TXI, narrow band imaging (NBI), and chromoendoscopy (CE).

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Background And Aim: Olympus Corporation released the texture and color enhancement imaging (TXI) technology as a novel image-enhancing endoscopic technique. We investigated the effectiveness of TXI in the imaging of serrated colorectal polyps, including sessile serrated lesions (SSLs).

Methods: Serrated colorectal polyps were observed using white light imaging (WLI), TXI, narrow-band imaging (NBI), and chromoendoscopy with and without magnification.

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