Synopsis of recent research by authors named "Chie Nishioka"
Chie Nishioka's research primarily focuses on the roles of thrombomodulin and various signaling pathways in leukemia and inflammation, demonstrating significant anti-inflammatory and cytoprotective effects in various experimental settings.
A notable finding includes the identification of G-protein coupled receptor 15 (GPR15) as a key mediator in thrombomodulin's protective functions and its potential interactions related to graft-versus-host disease and sepsis.
Additional studies highlight how microRNA and STAT5 signaling regulate adhesion molecules and gene expression in leukemia, contributing to a better understanding of treatment resistance and progression in acute myeloid leukemia (AML) and chronic myeloid leukemia (CML).
